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OPRL1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Marke: Proteintech 12970-1-AP-150UL
Additional Details : Gewicht : 0.00010kg
Beschreibung
The G-protein-coupled receptor (GPCR) superfamily is comprised of an estimated 600-1,000 members and is the largest known class of molecular targets with proven therapeutic value. The nociceptin receptor is a G-protein coupled opioid receptor that functions as receptor for the endogenous neuropeptide nociceptin. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling via G proteins mediates inhibition of adenylate cyclase activity and calcium channel activity. Arrestins modulate signaling via G proteins and mediate the activation of alternative signaling pathways that lead to the activation of MAP kinases. Plays a role in modulating nociception and the perception of pain. Plays a role in the regulation of locomotor activity by the neuropeptide nociceptin.Spezifikation
OPRL1 | |
Polyclonal | |
Unconjugated | |
OPRL1 | |
Kappa type 3 opioid receptor, KOR 3, Nociceptin receptor, NOCIR, OOR, opiate receptor like 1, OPRL1, ORL1, Orphanin FQ receptor | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
18389, 29256, 4987 | |
-20°C | |
Liquid |
Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot | |
0.13 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
P35370, P35377, P41146 | |
Oprl1 | |
OPRL1 Fusion Protein Ag4079 | |
150 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |