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Invitrogen™ OGT Polyclonal Antibody
Rabbit Polyclonal Antibody
Marke: Invitrogen™ PA522071
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Beschreibung
Recommended positive controls: 293T, A431, HeLa, HepG2, mouse brain, PC-12. Predicted reactivity: Mouse (100%), Rat (100%), Xenopus laevis (98%), Pig (100%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a glycosyltransferase that catalyzes the addition of a single N-acetylglucosamine in O-glycosidic linkage to serine or threonine residues. Since both phosphorylation and glycosylation compete for similar serine or threonine residues, the two processes may compete for sites, or they may alter the substrate specificity of nearby sites by steric or electrostatic effects. The protein contains multiple tetratricopeptide repeats that are required for optimal recognition of substrates. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Spezifikation
| OGT | |
| Polyclonal | |
| Unconjugated | |
| OGT | |
| 1110038P24Rik; 4831420N21Rik; AI115525; FLJ23071; HINCUT-1; HRNT1; MGC22921; O linked N-acetylglucosamine transferase; O-GLCNAC; o-glcnac transferase; O-GlcNAc transferase p110 subunit; O-GlcNAc transferase subunit p110; OGT; Ogtl; O-linked N-acetylglucosamine (GlcNAc) transferase; O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase); O-linked N-acetylglucosamine transferase; O-linked N-acetylglucosamine transferase 110 kDa subunit; UDP-N-acetylglucosamine:polypeptide-N- acetylglucosaminyl transferase; UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase; UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit; uridinediphospho-N-acetylglucosamine:polypeptide beta-N-acetylglucosaminyl transferase | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 108155, 26295, 8473 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry | |
| 1.51 mg/mL | |
| PBS with 20% glycerol and 0.025% ProClin 300; pH 7 | |
| O15294, P56558, Q8CGY8 | |
| OGT | |
| Recombinant protein encompassing a sequence within the center region of human O-GlcNAc transferase. The exact sequence is proprietary. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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