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Nitrofurantoin, 98 %, Thermo Scientific Chemicals

Artikelnummer. 11441077
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Artikelnummer. 11441077 Lieferant Thermo Scientific Alfa Aesar Lieferanten-Nr. B24079.36
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Beschreibung

CAS: 67-20-9 | C8H6N4O5 | 238.16 g/mol

Nitrofurantoin is a nitrofuran antibiotic that is used as a substrate of bacterial nitrofuran reductase to study the interactions of active metabolites with DNA, ribosomal proteins and metabolic and pro-oxidant processes. It is an antibactericidal compound that has been historically prepared by the reaction of 1-aminohydantoin sulfate and 5-nitro-2-furaldehyde diacetate. It shows activity against many Gram-positive and Gram-negative bacteria. Nitrofurantoin is effective against enterococci, staphylococci, streptococci, corneybacteria, many strains of Escherichia coli.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Nitrofurantoin is a nitrofuran antibiotic that is used as a substrate of bacterial nitrofuran reductase to study the interactions of active metabolites with DNA, ribosomal proteins and metabolic and pro-oxidant processes. It is an antibactericidal compound that has been historically prepared by the reaction of 1-aminohydantoin sulfate and 5-nitro-2-furaldehyde diacetate. It shows activity against many Gram-positive and Gram-negative bacteria. Nitrofurantoin is effective against enterococci, staphylococci, streptococci, corneybacteria, many strains of Escherichia coli.

Solubility
Soluble in water (<0.01g/100mL at 19°C), dimethyl sulfoxide and methanol.

Notes
Keep container tightly sealed. Store in cool, dry conditions in well sealed containers. Store under dry inert gas. It is hygroscopic in nature. Incompatible with oxidizing agents. It is sensitive to light.
TRUSTED_SUSTAINABILITY

Chemische Identifikatoren

CAS 67-20-9
Summenformel C8H6N4O5
Molekulargewicht (g/mol) 238.16
MDL-Nummer MFCD00003224
InChI-Schlüssel NXFQHRVNIOXGAQ-YCRREMRBSA-N
Synonym nitrofurantoin, macrodantin, 5-nitrofurantoin, furadantin, furadonine, nitrofurantoine, furadantine, furadantoin, furadoine, furadontin
PubChem CID 6604200
ChEBI CHEBI:71415
IUPAC-Name 1-[(E)-[(5-Nitrofuran-2-yl)methyliden]amino]imidazolidin-2,4-dion
SMILES [O-][N+](=O)C1=CC=C(O1)\C=N\N1CC(=O)NC1=O

Spezifikation

Chemischer Name oder Material Nitrofurantoin
Schmelzpunkt ∼265°C (decomposition)
Menge 500 g
Empfindlichkeit Hygroskopisch; lichtempfindlich
Löslichkeitsinformationen Soluble in water (<0.01g/100 ml at 19°C),dimethyl sulfoxide and methanol.
Formelmasse 238.16
Reinheit (%) 98%

RUO – Research Use Only

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