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  8. Nicotinamid, 99 %, Thermo Scientific Chemicals

Nicotinamid, 99 %, Thermo Scientific Chemicals

Artikelnummer. 11498536
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Product Code. 11498536 Supplier Thermo Scientific Alfa Aesar Supplier No. A15970.30
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Description

CAS: 98-92-0 | C6H6N2O | 122.127 g/mol

Nicotinamide is a building block (active component) of coenzymes nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phopshate (NADP). It may be used as a substrate of nicotinamide phosphoribosyltransferase (NAMPT, EC 2.4.2.12), the rate-limiting enzyme for NAD(+) biosynthesis and an important signaling molecule. It is an amide derivative of vitamin B3 and a PARP inhibitor.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Anwendungen
Nicotinamid ist ein Baustein (aktiver Bestandteil) der Coenzyme Nicotinamid Adenin Dinucleotid (NAD) und Nicotinamid Adenin Dinucleotid phopshat (NADP). Es kann als Substrat der Nicotinamid-Phosphoribosyltransferase (NAMPT, EC2.4.2.12), dem geschwindigkeitsbegrenzenden Enzym für die NAD(+)-Biosynthese und einem wichtigen Signalmolekül verwendet werden. Es ist ein Amid-Derivat von Vitamin B3 und ein PARP-Inhibitor.

Löslichkeit
Löslich in Wasser, Ethanol, Glycerin, DMSO, Methanol, Butanol und Chloroform. Schwer löslich in Äther.

Hinweise
Stabil unter empfohlenen Lagerbedingungen. Nicht kompatibel mit Oxidationsmitteln.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 98-92-0
Summenformel C6H6N2O
Molekulargewicht (g/mol) 122.127
MDL-Nummer MFCD00006395
InChI-Schlüssel DFPAKSUCGFBDDF-UHFFFAOYSA-N
Synonym nicotinamide, niacinamide, 3-pyridinecarboxamide, vitamin pp, nicotinic acid amide, papulex, aminicotin, amixicotyn, nicobion, nicotylamide
PubChem CID 936
ChEBI CHEBI:17154
IUPAC-Name Pyridin-3-carboxamid
SMILES C1=CC(=CN=C1)C(=O)N

Specifications

Chemischer Name oder Material Nicotinamide
Schmelzpunkt 128°C to 132°C
Dichte 1.4
Flammpunkt 182°C (360°F)
Prozentgehaltsbereich 99%
Menge 250 g
Beilstein 383619
Merck Index 14,6523
Löslichkeitsinformationen Soluble in water,ethanol ,glycerol,DMSO ,methanol,butanol and chloroform. Slightly soluble in ether.
Formelmasse 122.13
Reinheit (%) 99%
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Safety and Handling

compliance-icons
Product Identifier
  • Nicotinamide
 Signal Word
  • Achtung
 Hazard Category
  • Schwere Augenschädigung/Augenreizung Kategorie 2
 Hazard Statement
  • H319-Verursacht schwere Augenreizung.
 Precautionary Statement
  • P280-Schutzhandschuhe/Schutzkleidung/Augenschutz/Gesichtsschutz tragen.
  • P305+P351+P338-BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.
 Supplemental information
  • MIXTURE LIST-Contain: Nicotinamide
SDS

RUO – Research Use Only

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