NF-H Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Beschreibung

This antibody can recognize both NEFH and NEFM.

Involved in the maintece of neuronal caliber, neurofilaments are the intermediate filament proteins found specifically in neurons, and are composed predomitly of three major proteins called NF-L, NF-M and NF-H. Like most other intermediate filament proteins (IFPs), the expression of the different neuronal IFPs is both tissue-specific and developmentally regulated. NF-H has an important role in mature axons and is involved in amyotrophic lateral sclerosis (ALS).