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Nanog Mouse anti-Human, PE, Clone: N31-355, BD

Mouse Monoclonal Antibody

241.00 CHF - 540.00 CHF

Spezifikation

Antigen Nanog
Klon N31-355
Anwendungen Flow Cytometry
Klassifikation Monoclonal
Konjugat PE
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Produkte 2
Produktcode Marke Menge Preis Menge & Verfügbarkeit  
Produktcode Marke Menge Preis Menge & Verfügbarkeit  
15820559
Unterlagen ansehen Aktionsdetails
BD Biosciences
560873
25 Tests
241.00 CHF
1 Stück
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Verfügbar ab: 22-04-2024
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15830239
Unterlagen ansehen Aktionsdetails
BD Biosciences
560483
100 Tests
540.00 CHF
1 Stück
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»
Verfügbar ab: 16-04-2024
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Beschreibung

Beschreibung

The N31-355 monoclonal antibody reacts with human Nanog (named for Tir Na Nog, the land of the ever-young of Celtic mythology), which is a homeobox transcription factor required for the maintenance of the undifferentiated state of pluripotent stem cells. Nanog expression counteracts the differentiation-promoting signals induced by the extrinsic factors LIF (Leukemia Inhibitory Factor) and BMP (Bone Morphogenic Protein). When Nanog expression is down-regulated, cell differentiation can proceed. Proteins that regulate Nanog expression include transcription factors Oct4, SOX2, FoxD3, and Tcf3 and tumor suppressor p53. Nanog is one of the factors that can contribute to reprogramming of differentiated cells to an induced pluripotent stem cell state.

Spezifikation

Spezifikation

Nanog
Flow Cytometry
PE
RUO
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
IgG1 κ
Affinity Purified
N31-355
Monoclonal
Mouse
Human
Human Nanog Recombinant Protein
Primary
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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For Research Use Only.