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Myogenin Monoclonal Antibody (F5D), eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

Marke:  Affymetrix eBioscience 14-5643-82

458.85 CHF gültig bis 2024-03-29
Benutzen Sie den Promotions-Code "21653" um Ihren Promotions-Preis zu erhalten.



Additional Details : Gewicht : 0.01000kg

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Artikelnummer. 15237427

  • 483.00 CHF / 100 Mikrogramm
Verfügbar ab: 12-04-2024
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Beschreibung

Beschreibung

Description: This F5D monoclonal antibody reacts with human, mouse, dog, and rat myogenin, a 34-kDa transcription factor. Expressed in skeletal and heart muscle, myogenin is a member of the MyoD family of basic-helix-loop-helix proteins, which also includes MyoD, Myf5, and MRF4. This transcription factor interacts with other helix-loop-helix proteins, which may or may not be muscle-specific. Myogenin plays a significant role in myogenic differentiation, even directing nonmuscle cells to the myogenic lineage. Transforming growth factor-beta (TGFb) and bone morphogenetic protein-2 (BMP2) inhibit myogenin transcriptional activity. Predomitly residing within the nucleus, the subcellular localization of myogenin has been shown to be dependent on differentiation status and cell density. For instance, trafficking of myogenin between the nucleus and cytoplasm has been reported during skeletal muscle differentiation to mediate transcription control. Applications Reported: This F5D antibody has been reported for use in immunoblotting (WB) and immunocytochemistry. Applications Tested: This F5D antibody has been tested by western blot and immunocytochemistry of the C2C12 cell line. This can be used at less than or equal to 1-5 μg/mL for both applications. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Purity: Greater than 90%, as determined by SDS-PAGE. Aggregation: Less than 10%, as determined by HPLC.

Myogenin is a muscle-specific transcription factor that can induce myogenesis in a variety of cell types in tissue culture. It is a member of a large family of proteins related by sequence homology, the helix-loop-helix proteins. It is essential for the development of functional skeletal muscle.
Spezifikation

Spezifikation

Myogenin
Monoclonal
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.2
P12979, P15173, P20428
MYOG
Affinity chromatography
RUO
17928, 29148, 4656, 490224
4° C
Liquid
Immunocytochemistry, Western Blot
F5D
Unconjugated
MYOG
bHLHc3; Class C basic helix-loop-helix protein 3; MYF4; Myf-4; myo; MYOD1-related protein; MYOG; Myogenic factor 4; Myogenic factor-4; myogenin; myogenin (myogenic factor 4)
Mouse
100 μg
Primary
Canine, Human, Mouse, Rat
Antibody
IgG1
Produktvorschläge

Produktvorschläge

Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Zertifikate
Sonderangebote

Sonderangebote

For Research Use Only.