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Invitrogen™ MT-ND5 Polyclonal Antibody

Description
Positive Samples: Mouse heart, Mouse brain, Rat brain; Cellular Location: Mitochondrion inner membrane, Multi-pass membrane protein Immunogen sequence: IALELNNLTM KLSMNKANPY SSFSTLLGFF PSIIHRITPM KSLNLSLKTS LTLLDLIWLE KTIPKSTSTL HTNMTTLTTN QKGLIKLYFM SFLINIILII ILYSINLE.
A small number of complex I subunits are the products of mitochondrial genes (subunits 1-7), while the remainder are nuclear encoded and imported from the cytoplasm. NADH dehydrogenase subunit 5 (ND5) is most likely a component of the hydrophobic protein fragment of Complex I. Mutations in the gene encoding for ND5 are implicated in Mitochondrial neurogastrointestinal encephalomyopathy, an autosomal recessive multisystem disorder that results in dramatically elevated levels of circulating thymidine and deoxyuridine.
Specifications
Specifications
| Antigen | MT-ND5 |
| Anwendungen | ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry |
| Klassifikation | Polyclonal |
| Konzentration | 2.75 mg/mL |
| Konjugat | Unconjugated |
| Zusammensetzung | PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 |
| Gen | MT-ND5 |
| Gen-Zugriffsnummer | P03915, P03921, P11661 |
| Gen-Alias | mitochondrially encoded NADH dehydrogenase 5; MTND5; mt-Nd5; NADH Dehydrogenase 5; NADH dehydrogenase subunit 5; NADH5; NADH-ubiquinone oxidoreductase chain 5; ND5 |
| Gensymbole | MT-ND5, ND5 |
| Show More |
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