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ACROBiosystems Mouse CD28 Protein, His Tag
Brand: ACROBiosystems CD8-M52H6-1MG
Additional Details : Gewicht : 0.00001kg
Description
T-cell-specific surface glycoprotein CD28 is also known as TP44, is a single-pass type I membrane protein which contains one Ig-like V-type (immunoglobulin-like) domain. is one of the molecules expressed on T cells that provide co-stimulatory signals, which are required for T cell activation. CD28 is the receptor for CD80 (B7.1) and CD86 (B7.2). When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting cells is constitutive. CD28 is the only B7 receptor constitutively expressed on naive T cells.
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 16.9 kDa. The protein migrates as 30-35 kDa and 55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Specifications
| NP_031668.3 | |
| 1 mg | |
| Asn 20 - Lys 149 | |
| CD28,Tp44 | |
| Unconjugated | |
| His Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >90% as determined by SDS-PAGE |
| 16.9 kDa | |
| Mouse CD28, His Tag (CD8-M52H6) is expressed from human 293 cells (HEK293). It contains AA Asn 20 - Lys 149 (Accession # P31041-1). | |
| -20°C | |
| CD28 | |
| Mouse | |
| PBS, pH7.4 | |
| HEK293 | |
| Immune Checkpoint Proteins |