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CD206 Mouse anti-Human, BUV395, Clone: 19.2, BD Optibuild™

Mouse Monoclonal Antibody

Marke:  BD Biosciences 740309

Additional Details : Gewicht : 0.01000kg

Artikelnummer. 15806679

  • 935.00 CHF / 1 Stück
Verfügbar ab: 23-04-2024
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Beschreibung

Beschreibung

The 19.2 monoclonal antibody specifically binds to CD206 which is also known as the macrophage mannose receptor (MMR) or C-type lectin domain family 13 member D (CLEC13D). CD206 is a type I transmembrane glycoprotein of approximately 162 kDa which binds to glycoconjugates containing mannose, fucose, or N-acetylglucosamine. These carbohydrates are present on the surface of many microorganisms and enable the macrophage to bind to microorganisms through the MMR and internalize them during the process of phagocytosis. CD206 is expressed on human macrophages, endothelial cells, and cultured dendritic cells. It is not detected on resting monocytes. Mannose receptor expression is upregulated on peripheral blood mononuclear cells following 3 day incubation with GM-CSF.

The antibody was conjugated to BD Horizon™ BUV395 which is part of the BD Horizon Brilliant™ Ultraviolet family of dyes. This dye has been exclusively developed by BD Biosciences to have minimal spillover into other detectors, making it an optimal choice for multicolor flow cytometry. With an Ex Max at 348nm and an Em Max at 395nm, BD Horizon BUV395 can be excited with a 355nm laser and detected with a 379/28 filter.

Spezifikation

Spezifikation

CD206
Monoclonal
0.2mg/mL
Macrophage mannose receptor; MMR; MRC1; CLEC13D
Mouse
Affinity Purified
RUO
Human
IgG1 κ
Flow Cytometry
19.2
Brilliant Ultraviolet 395
Aqueous buffered solution containing ≤0.09% sodium azide.
Human Placental Macrophage Mannose Receptor
50 μg
Primary
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Produktvorschläge

Produktvorschläge

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Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Zertifikate
Sonderangebote

Sonderangebote

For Research Use Only