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MMP13 Rabbit anti-Human, Mouse, Rat, Zebrafish, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Marke: Proteintech 18165-1-AP-20UL
Additional Details : Gewicht : 0.00010kg
Beschreibung
MMP13 (collagense 3) plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC, and ACAN. MMP13 cleaves tripal helical collagens, including type I, II, and III collagen - but has the highest activity with soluble type II collagen. It can degrade collagen type IV, XIV, and X. MMP13 plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization, and ossification. It is required for normal embryonic bone development and ossificaiton. Mutations affecting the gene can lead to spondyloepimetaphyseal dysplasia Missouri type, metaphyseal anadysplasia 1, and metaphyseal dysplasia Sphar type.Spezifikation
MMP13 | |
Polyclonal | |
Unconjugated | |
MMP13 | |
CLG3, Collagenase 3, Matrix metalloproteinase 13, MMP 13, MMP13 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
171052, 17386, 387293, 4322 | |
-20°C | |
Liquid |
Western Blot, Immunoprecipitation, Immunofluorescence, Immunocytochemistry, Immunohistochemistry (Paraffin) | |
0.27 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
P23097, P33435, P45452 | |
Mmp13, mmp13a | |
MMP13 Fusion Protein Ag12653 | |
20 μL | |
Primary | |
Mouse, Human, Zebrafish, Rat | |
Antibody | |
IgG |