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MHC Class II (I-A) Rat anti-Mouse, FITC, Clone: NIMR-4, eBioscience™

Rat Monoclonal Antibody

Marke:  Affymetrix eBioscience 11-5322-82

Additional Details : Gewicht : 0.25000kg

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Artikelnummer. 15228239

  • 183.00 CHF / 100 Mikrogramm


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Beschreibung

Beschreibung

MHC class II molecules are heterodimers of non-covalently associated alpha (31-34 kDa) and beta (26-29 kDa) chains. Major histocompatibility complex class II antigen presentation requires the participation of lysosomal proteases in two convergent processes. First, the antigens endocytosed by the antigen presenting cells must be broken down into antigenic peptides. Second, class II molecules are synthesized with their peptide-binding site blocked by invariant chain (Ii), and they aquire the capacity to bind antigens only after Ii has been degraded in the compartments where peptides reside. MHC class II molecules present exogenously derived antigen to CD4+ T lymphocytes, which are usually T helper cells. CD4 interacts with non-polymorphic residues of MHC class II.
Spezifikation

Spezifikation

MHC Class II (I-A)
Monoclonal
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.2
P06342
H2-Ab1
IgG2b
100 μg
4° C, store in dark, DO NOT FREEZE!
Primary
14961
Flow Cytometry
NIMR-4
FITC
H2-Ab1
Liquid
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Mouse
Videos
Dokumentation

For Research Use Only.