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mGluR1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marke:  Proteintech 19955-1-AP-20UL

Additional Details : Gewicht : 0.00010kg

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Artikelnummer. 16839434

  • 131.19 CHF / 20 Mikroliter

Verfügbar ab: 28-06-2022
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Beschreibung

Beschreibung

The antibody can recognize isoform1 and isoform2 of GRM1.

Glutamate is the main excitatory neurotransmitter in the brain. For many years it had been considered to act only on the ligand-gated receptor channels-termed NMDA, AMPA and kainite receptors that are involved in the fast excitatory synaptic transmission. Recently, glutamate has been shown to regulate enzymes producing second messengers via specific receptors coupled to G-proteins. These receptors are called metabotropic glutamate receptors. In expression systems, Group-I receptors stimulate phospholipase C as revealed by an increase in phosphoinositide turnover and calcium release from internal stores. Group-II and -III receptors are coupled to the inhibition of adenylyl cyclase. The Group-I receptors include mGluR1a and mGluR5. The Group-II receptors in include mGluR2 and mGluR3.
Spezifikation

Spezifikation

mGluR1
Polyclonal
Unconjugated
GRM1
GPRC1A, GRM1, GRM1A, mGlu1, mGluR1, MGLUR1A
Rabbit
Antigen Affinity Chromatography
RUO
14816, 2911
Antibody
IgG
Immunofluorescence, Flow Cytometry, Immunohistochemistry (Paraffin), Immunocytochemistry
0.17 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P97772, Q13255
GRM1
Peptide
20 μL
Primary
Human, Mouse
Liquid
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation
Zertifikate
Sonderangebote

Sonderangebote