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  4. Invitrogen™ Human MET [M1250T], His Tag Recombinant Protein

Invitrogen™ Human MET [M1250T], His Tag Recombinant Protein

Codice prodotto. 10007092
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Menge:
1 mg
100 μg
Dimensione della confezione:
1 Milligramm
100 Mikrogramm
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Codice prodotto. 10007092

Marca: Invitrogen™ PV4272

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Les retours ne sont pas autorisés pour ce produit. Consulta la politica di reso

Descrizione

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Cytoplasmic

MET (cMET) is a receptor-like tyrosine kinase whose dysregulation has been linked to many types of human malignancies. After activation of the ligand, MET interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, and STAT3. There interactions lead to the activation of signaling cascades including RAS-ERK, PI3, kinase-AKT, and PLCgamma-PKC. MET plays a role in embryonic development including gastrulation, development of muscles and neurons, angiogenesis, and kidney formation. It also plays a role in adults including wound healing, organ regeneration, and tissue remodeling. MET has been linked to cancers including gastric, renal, and breast; therefore, making it a target for cancer therapeutics and diagnostic testing.
TRUSTED_SUSTAINABILITY

Specifica

Konzentration See Label
Zur Verwendung mit (Anwendung) Kinase Assay
Zusammensetzung 50 mM tris HCl with 0.02% Triton X-100, 0.5 mM EDTA, 150 mM NaCl, 2 mM DTT, 50% glycerol and no preservative; pH 7.5
Molekulargewicht 53.7 kDa
Name Human MET [M1250T], His Tag
Menge 1 mg
Kennzeichnung RUO - research use only
Gebräuchliche Bezeichnung MET (M1250T Mutant)
Kinase-Familie MET (HGFR) Kinase Family
Proteinlänge 956-1390; M1250T
Konjugat Unconjugated
Spezies Human
Rekombinant Recombinant
Proteinmarkierung His-tag
Inhalt und Lagerung -80°C, Avoid Freeze/Thaw Cycles
Expressionssystem Insect cells
Form Liquid
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Titolo del prodotto

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