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MEF2C Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Marke: Proteintech 18290-1-AP-20UL
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Beschreibung
The antibody can recognize the transcript variant 1 and transcript variant 3 of MEF2C.
MEF2C is a transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex. Necessary for proper development of megakaryocytes and platelets and for bone marrow B lymphopoiesis. Required for B-cell survival and proliferation in response to BCR stimulation, efficient IgG1 antibody responses to T-cell-dependent antigens and for normal induction of germinal center B cells. May also be involved in neurogenesis and in the development of cortical architecture. Isoform 3 and isoform 4, which lack the repressor domain, are more active than isoform 1 and isoform 2.Spezifikation
MEF2C | |
Polyclonal | |
Unconjugated | |
MEF2C | |
MEF2C, myocyte enhancer factor 2C | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
17260, 4208, 499497 | |
-20°C | |
Liquid |
Western Blot, Immunohistochemistry (Paraffin) | |
0.26 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
Q06413, Q8CFN5 | |
Mef2c | |
Peptide | |
20 μL | |
Primary | |
Mouse, Rat, Human | |
Antibody | |
IgG |
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MEF2C Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech > 20 μL; Unconjugated
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