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Ly-108 Mouse anti-Mouse, APC, Clone: eBio13G3-19D (13G3-19D), eBioscience™

Mouse Monoclonal Antibody

Marke:  Affymetrix eBioscience 17-1508-82

Additional Details : Gewicht : 0.25000kg

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Artikelnummer. 15320690

  • 317.00 CHF / 100 Mikrogramm


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Beschreibung

Beschreibung

Description: The eBio13G3-19D monoclonal antibody reacts with mouse Ly108, the mouse homologue of human SLAMF6 (signaling lymphocyte activation molecule family member 6). Mouse Ly108 is also known as NTB-A (NK cell, T cell, B cell antigen), and is expressed on NK, T cells, and B cells. Engagement of the Ly108 receptor enhances NK cell activity and expression of IFN-gamma, and contributes to the inability of NK cells to kill Epstein Barr virus-infected B cells in X-linked lymphoproliferative disease. CD4+ T cells from Ly108 knock-out mice exhibit diminished ability to produce IL-4 and defective neutrophil functions. Staining has not revealed any strain differences between C57BL/6 and BALB/c mice. Other strains have not been tested. Applications Reported: This eBio13G3-19D (13G3-19D) antibody has been reported for use in flow cytometric analysis. Applications Tested: This eBio13G3-19D (13G3-19D) antibody has been tested by flow cytometric analysis of mouse splenocytes. This can be used at less than or equal to 0.25 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser. Filtration: 0.2 μm post-manufacturing filtered.

Ly108 is the mouse homologue of human SLAMF6 (signaling lymphocyte activation molecule family member 6). Mouse Ly108 is expressed on NK, B cells, and T cells. Activation of Ly108 receptor enhances NK cell activity and IFN-gamma expression.
Spezifikation

Spezifikation

Ly-108
Monoclonal
0.2 mg/mL
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
Q9ET39
SLAM family member 6, Activating NK receptor, NK-T-B-antigen, NTB-A, CD352, SLAMF6, KALI, UNQ6123/PRO20080
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Mouse
Flow Cytometry
eBio13G3-19D (13G3-19D)
APC
Slamf6
Liquid
Slamf6
IgG2a, kappa
100 μg
4° C, store in dark, DO NOT FREEZE!
Primary
30925
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

For Research Use Only.