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Invitrogen™ LRRK2 (WT) Recombinant Protein

Artikelnummer. 15393806
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1 Milligramm
10 Mikrogramm
100 Mikrogramm
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15393806 100 μg 100 Mikrogramm
15383806 10 μg 10 Mikrogramm
15303816 1 mg 1 Milligramm
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Artikelnummer. 15393806 Lieferant Invitrogen™ Lieferanten-Nr. A15198

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Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. This full-length, purified and active wild-type LRRK2 protein may be useful in research to better understand the native protein, unaffected by mutations, as well as to explore the mechanisms underlying the disease. Increase disease relevance by interrogating a purified and active full-length LRRK2 protein Uncover novel compounds or hits specific to the full-length form Advance Parkinson's research using the full-length protein and validated assays Related Links:LRRK2 Tools for Advancing Parkinson's Disease ResearchLanthaScreen™ Kinase Activity AssayLanthaScreen™ Eu Kinase Binding Assay Protein Form: Recombinant, Full Length.

LRRK2 (Leucine Rich Repeat Kinase 2) is a Protein Coding gene. Diseases associated with LRRK2 include Parkinson Disease 8, Autosomal Dominant and Hereditary Late-Onset Parkinson Disease. Among its related pathways are Signaling by PTK6 and ncRNAs involved in Wnt signaling in hepatocellular carcinoma. Gene Ontology (GO) annotations related to LRRK2 (G2019S Mutant) include protein homodimerization activity and transferase activity, transferring phosphorus-containing groups. An important paralog of LRRK2 (G2019S Mutant) is TNNI3K. Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene, which codes for a multidomain protein kinase, are considered the most common genetic cause of late-onset autosomal-dominant Parkinson's disease.
TRUSTED_SUSTAINABILITY

Spezifikation

Zugriffsnummer Q5S007
Konzentration See Label
Zur Verwendung mit (Anwendung) Kinase Assay
Zusammensetzung Proprietary buffer with no preservative
Gen-ID (Entrez) 120892
Molekulargewicht 288 kDa
Name LRRK2 (WT)
Reinigungsverfahren Purified
Menge 100 μg
Lagerungsbedingungen -80°C, Avoid Freeze/Thaw Cycles
Kennzeichnung RUO
Gen-Alias LRRK2
Gebräuchliche Bezeichnung LRRK2 (WT)
Gensymbol LRRK2
Kinase-Familie LRRK Kinase Family
Produkttyp Protein
Konjugat Unconjugated
Spezies Human
Rekombinant Recombinant
Proteinmarkierung DYKDDDDK-tag
Sequenz Full length
Inhalt und Lagerung -80°C, Avoid Freeze/Thaw Cycles
Expressionssystem Baculovirus
Proteinfamilie Kinases & Inhibitors
Proteinform Recombinant, Full Length
Form Liquid
Forschungskategorie Neurobiology
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