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LRRK2 [I2020T] Human Protein

LRRK2 [I2020T] Human Protein

Marke:  Invitrogen PV5854

Additional Details : Gewicht : 0.00010kg

Artikelnummer. 10268044

  • 842.00 CHF / 1 Stück
Verfügbar ab: 18-04-2024
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Beschreibung

Beschreibung

LRRK2 is a multidomain protein that includes a kinase domain, a GTPase domain, and a leucine-rich repeat (LRR) domain. Mutations in this gene have been associated with Parkinson's disease, including the I2020T mutation in the kinase catalytic domain.

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  • Spezifikation

    Spezifikation

    NP_940980.2
    Pharma and Biopharma, Protein Assays and Analysis, Kinase Assay
    205kDa
    10μg
    For research use only. Not for use in diagnostic procedures
    LRRK2 I2020T
    LRRK2 I2020T was pre-diluted in enzyme dilution buffer and assayed in 20mM Tris (pH 7.5), 10mM MgCl2, 1mM EGTA, 1mM Na3VO4, 5mM β- glycerophosphate, 2mM DTT, 0.02% Polysorbate 20, 100μM ATP, 250μM ERM (LRRKtide) peptide substrate (RLGRDKYKTLRQIRQ) (PV5093) and trace [32P]-γ-ATP for 10 minutes at 30°C
    Amino acids 970-2527
    21nmoles of phosphate transferred to ERM (LRRKtide) peptide substrate (RLGRDKYKTLRQIRQ) (PV5093) per minute per mg of total protein at 30°C. Activity determined at a final protein concentration of 2.08μg/mL
    GST Tag
    Kinase and inhibitors
    Serine/threonine kinase
    0.28mg/mL
    Frozen
    LRRK2 [I2020T] Human Protein
    –80°C
    1 Each
    LRRK2 [I2020T] Human Protein
    LRRK
    LRRK2 [I2020T] Human Protein
    Human
    Baculovirus
    Frozen
    85% by SDS-PAGE
    Produktvorschläge

    Produktvorschläge

    Videos
    Sicherheitsdatenblatt (SDS)
    Dokumentation

    Dokumentation

    Zertifikate
    Sonderangebote

    Sonderangebote

    For Research Use Only. Not for use in diagnostic procedures.