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Lovastatin, 97%, Thermo Scientific™
97.89 CHF - 359.55 CHF
Chemische Identifikatoren
| CAS | 75330-75-5 |
|---|---|
| Summenformel | C24H36O5 |
| Molekulargewicht (g/mol) | 404.55 |
| MDL-Nummer | MFCD00072164 |
| InChI-Schlüssel | PCZOHLXUXFIOCF-BXMDZJJMSA-N |
| Synonym | lovastatin, mevinolin, mevacor, monacolin k, lovalip, altoprev, lovalord, mevinacor, nergadan, 6alpha-methylcompactin |
| PubChem CID | 53232 |
| ChEBI | CHEBI:40303 |
| IUPAC-Name | (1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-methylbutanoate |
| SMILES | CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12 |
| Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
|---|---|---|---|---|---|---|---|---|---|
| Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
|
15489537
|
Thermo Scientific Alfa Aesar
H52792.06 |
5g |
 107.00 CHF 97.89 CHF / 5 Gramm Sparen 9.11 CHF 8% Rabatt |
Log in om dit product te kopen Registreer vandaag om een webaccount aan te maken | |||||
|
15499537
|
Thermo Scientific Alfa Aesar
H52792.14 |
25g |
388.00 CHF 359.55 CHF / 25 Gramm Sparen 28.45 CHF 7% Rabatt |
Log in om dit product te kopen Registreer vandaag om een webaccount aan te maken | |||||
Beschreibung
This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.
ApplicationsLovastatin is a cholesterol lowering drug and competitive inhibitor of HMG-CoA reductase, a rate limiting enzyme in cholesterol synthesis. Blocks the production of mevalonate, a critical compound in the production of cholesterol and isoprenoids. It increases cellular resistance to anticancer agents such as doxorubicin and induces apoptosis in myeloma cells. It causes cell cycle arrest in G1 and G2/M phases.
Solubility
Soluble in DMSO (10 mg/ml), ethanol (10 mg/ml), methanol, chloroform, acetone, acetonitrile, DMF, and water (0.4 µg/ml).
Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents and heat.
Chemische Identifikatoren
| 75330-75-5 | |
| 404.55 | |
| PCZOHLXUXFIOCF-BXMDZJJMSA-N | |
| 53232 | |
| (1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-methylbutanoate |
| C24H36O5 | |
| MFCD00072164 | |
| lovastatin, mevinolin, mevacor, monacolin k, lovalip, altoprev, lovalord, mevinacor, nergadan, 6alpha-methylcompactin | |
| CHEBI:40303 | |
| CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12 |
Spezifikation
| Lovastatin | |
| C24H36O5 | |
| lovastatin, mevinolin, mevacor, monacolin k, lovalip, altoprev, lovalord, mevinacor, nergadan, 6alpha-methylcompactin | |
| PCZOHLXUXFIOCF-BXMDZJJMSA-N | |
| (1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-methylbutanoate | |
| 53232 | |
| 404.56 |
| 75330-75-5 | |
| MFCD00072164 | |
| Soluble in DMSO (10mg/ml),ethanol (10mg/ml),methanol,chloroform,acetone,acetonitrile,DMF,and water (0.4 μg/ml). | |
| CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12 | |
| 404.55 | |
| CHEBI:40303 | |
| 97% |
Sicherheit und Handhabung
GHS H Statement
H302-H315-H319-H335
Harmful if swallowed.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
P201-P202-P261-P272-P280g-P281-P302+P352-P308+P313-P333+P313-P363-P501c
H317-H351-H361d
missing translation for 'rtecsNumber' : EK7907000
missing translation for 'tsca' : No
Recommended Storage : Ambient temperatures
RUO – Research Use Only
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