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JSRP1 Monoclonal Antibody (6A9), Invitrogen™
Mouse Monoclonal Antibody
Marke: Invitrogen MA524513
Additional Details : Gewicht : 0.01000kg
Beschreibung
Peptide Sequence: MSMTTRAWEE LDGGLGSCQA LEDHSALAET QEDRASATPR LADSGSVPHD SQVAEGPSVD TRPKKMEKEP AARGTPGTGK ERLKAGASPR SVPARKKAQT
The junction between the transverse tubules (T-tubules) and the sarcoplasmic reticulum (SR) of skeletal muscle is called the triad. At the triad, dihydropyridine receptors (DHPR) of the T-tubule serve as voltage sensors in excitation-contraction coupling, while ryanodine receptors (RyR), the calcium release channels, exist in the membrane of the terminal cisternae of the SR. It is thought that during slow phase depolarization of the T-tubule, a third protein, triadin (95 kDa) transmits electrochemical signals to the SR through direct interaction with both DHPR and RyR. Another skeletal muscle specific 90 kDa protein has also been localized to the this junction. This protein is phosphorylated by an intrinsic protein kinase in triads suggesting that it may play an important regulatory or structural role in the skeletal muscle triad junction.Spezifikation
JSRP1 | |
Monoclonal | |
Unconjugated | |
JSRP1 | |
2300003C06Rik; 2310032K21Rik; homolog of mouse skeletal muscle sarcoplasmic reticulum protein JP-45; JP45; JP-45; Jsrp1; Junctional sarcoplasmic reticulum protein 1; Junctional SR; junctional-face membrane protein of 45 kDa homolog; skeletal muscle sarcoplasmic reticulum protein JP-45 | |
Mouse | |
Protein A | |
RUO | |
126306 | |
-20° C, Avoid Freeze/Thaw Cycles | |
Liquid |
ELISA, Western Blot | |
6A9 | |
PBS with no preservative; pH 7.4 | |
Q96MG2 | |
JSRP1 | |
JSRP1 (NP_653217.1, 1 a.a. ∽ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. | |
100 μg | |
Primary | |
Human | |
Antibody | |
IgG2a κ |