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JAKMIP1 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marke: Invitrogen PA534495
Additional Details : Gewicht : 0.01000kg
Beschreibung
A suggested positive control is rat brain tissue lysate. PA5-34495 can be used with blocking peptide PEP-1537.
JAKMIP1, also known as Marlin-1, is a highly-conserved vertebrate-specific microtubule-associated protein that plays a role in JAK1 signaling and regulate microtubule cytoskeleton rearrangements. JAKMIP1 is expressed predominantly in neuronal and lymphoid cells and colocalizes with microtubules. Multiple isoforms of JAKMIP1 are known to exist: isoforms 1 and 5 are also expressed in liver, lung and skeletal muscle, while isoforms 2-4 are specifically expressed in brain and retina. JAKMIP1 participates in polarized secretion in lymphocytes and it has been suggested to be a novel effector memory gene restraining T cell-mediated cytotoxicity. Dysregulation of JAKMIP1 gene expression is associated with genetic conditions linked to autism in humans.Spezifikation
JAKMIP1 | |
Polyclonal | |
Unconjugated | |
JAKMIP1 | |
5830437M04Rik; C330021K24Rik; FLJ31564; GABA-B receptor-binding protein; Gababrbp; gamma-aminobutyric acid (GABA-B) receptor binding protein; Jak and microtubule interacting protein 1; Jakmip1; JAMIP1; janus kinase and microtubule interacting protein 1; janus kinase and microtubule-interacting protein 1; MARLIN1; Marlin-1; Multiple alpha helices and RNA-linker protein 1; multiple alpha-helices and RNA-linker protein 1; multiple coiled-coil GABABR1-binding protein | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
152789, 305434, 76071 | |
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C | |
Liquid |
Western Blot | |
1 mg/mL | |
PBS with 0.02% sodium azide | |
Q3SWS9, Q8BVL9, Q96N16 | |
JAKMIP1 | |
A 16 amino acid peptide near the center of human JAKMIP1 | |
100 μg | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |