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J Chain Monoclonal Antibody (Mc19-9), Invitrogen™
Mouse Monoclonal Antibody
Marke: Invitrogen MA180527
Additional Details : Gewicht : 0.01000kg
Beschreibung
This antibody does not detect J chain in intact IgM in ELISA Assays due to steric hindrance. In Western Blotting techniques MA1-80527 detects J chain in IgM only under reducing conditions. Mouse anti Human J chain antibody, clone Mc19-9 reacts with human J chain as tested by ELISA using purified human Ig fragments as the solid phase target antigen.
J chain is a small glycopeptide and is structurally unrelated to heavy or light chains, but is synthesized by all plasma cells that secrete polymeric immunoglobulins. J chain is linked to IgA and IgM by disulfide bonds, however, it has been detected in IgG- and IgD-containing cells. J chains are present in a large proportion of the immunoglobulin-positive cells in the germinal centers of the tonsil and lymph node. B cells secrete J chain at an early stage of differentiation with the expression persisting in those cells destined to produce IgA or IgM.Spezifikation
| J Chain | |
| Monoclonal | |
| 1 mg/mL | |
| TBS with <0.1% sodium azide | |
| P01591 | |
| JCHAIN | |
| Human J Chain. | |
| 200 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
| ELISA, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot | |
| Mc19-9 | |
| Unconjugated | |
| JCHAIN | |
| 9530090F24Rik; AI323815; IGCJ; Igj; IgJ chain; immunoglobulin J chain; immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides; immunoglobulin joining chain; immunoglobulin joining gene (not J region); J chain; Jch; JCHAIN; Joining chain of multimeric IgA and IgM | |
| Mouse | |
| Protein A | |
| RUO | |
| 3512 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |