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Itraconazole, 98%

Product Code. 15497729
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25 g
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15497729 5 g 5g
15407739 25 g 25g
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Product Code. 15497729 Supplier Thermo Scientific Alfa Aesar Supplier No. J66390.06
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Verfügbar ab: 20-11-2026
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Description

CAS: 84625-61-6 | C35H38Cl2N8O4 | 705.64 g/mol

Itraconazole is a triazole antifungal agent. It is used to inhibit cytochrome P-450-dependent enzymes and ergosterol synthesis. It has been used against histoplasmosis, blastomycosis, cryptococcal meningitis, and aspergillosis. It?s different formulations are used to study Candida strains in murine invasive infections. It has been used to study proliferative changes of the forestomach mucosa in alloxan-induced diabetic rats..

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Itraconazole is a triazole antifungal agent. It is used to inhibit cytochrome P-450-dependent enzymes and ergosterol synthesis. It has been used against histoplasmosis, blastomycosis, cryptococcal meningitis, and aspergillosis. It′s different formulations are used to study Candida strains in murine invasive infections. It has been used to study proliferative changes of the forestomach mucosa in alloxan-induced diabetic rats..

Solubility
Insoluble in water. Solube in chloroform at 50 mg/ml. Slightly soluble in ethanol or methanol

Notes
Research Use only: Not intended for animal or human diagnostic or therapeutic use.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 84625-61-6
Formula molecolare C35H38Cl2N8O4
Molecular Weight (g/mol) 705.64
Numero MDL MFCD00870168,MFCD00941396
InChI Key VHVPQPYKVGDNFY-ZPGVKDDISA-N
Sinonimo Oriconazole; R51211
PubChem CID 45039617
IUPAC Name 1-(butan-2-yl)-4-{4-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-[(1H-1,2,4-triazol-1-yl)methyl]-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-4,5-dihydro-1H-1,2,4-triazol-5-one
SMILES CCC(C)N1N=CN(C1=O)C1=CC=C(C=C1)N1CCN(CC1)C1=CC=C(OC[C@H]2CO[C@@](CN3C=NC=N3)(O2)C2=CC=C(Cl)C=C2Cl)C=C1

Specifications

Materiale o nome chimico Itraconazole
Tipo Itraconazole
Forma fisica Powder
Punto di fusione 166°C
Colore White
Quantità 5 g
Punto d'infiammabilità >110°C (230°F)
Indice di Merck 14,5245
Informazioni di solubilità Insoluble in water; Solube in chloroform at 50mg/ml; Slightly soluble in ethanol or methanol
Peso formulazione 705.63
Percent Purity 98%
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RUO – Research Use Only

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