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Itraconazole, 98%

Code produit 15497729
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25 g
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15497729 5 g 5g
15407739 25 g 25g
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Product Code. 15497729 Supplier Thermo Scientific Alfa Aesar Supplier No. J66390.06
 Article restreint
Verfügbar ab: 20-11-2026
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Description

CAS: 84625-61-6 | C35H38Cl2N8O4 | 705.64 g/mol

Itraconazole is a triazole antifungal agent. It is used to inhibit cytochrome P-450-dependent enzymes and ergosterol synthesis. It has been used against histoplasmosis, blastomycosis, cryptococcal meningitis, and aspergillosis. It?s different formulations are used to study Candida strains in murine invasive infections. It has been used to study proliferative changes of the forestomach mucosa in alloxan-induced diabetic rats..

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Itraconazole is a triazole antifungal agent. It is used to inhibit cytochrome P-450-dependent enzymes and ergosterol synthesis. It has been used against histoplasmosis, blastomycosis, cryptococcal meningitis, and aspergillosis. It′s different formulations are used to study Candida strains in murine invasive infections. It has been used to study proliferative changes of the forestomach mucosa in alloxan-induced diabetic rats..

Solubility
Insoluble in water. Solube in chloroform at 50 mg/ml. Slightly soluble in ethanol or methanol

Notes
Research Use only: Not intended for animal or human diagnostic or therapeutic use.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 84625-61-6
Formule moléculaire C35H38Cl2N8O4
Poids moléculaire (g/mol) 705.64
Numéro MDL MFCD00870168,MFCD00941396
Clé InChI VHVPQPYKVGDNFY-ZPGVKDDISA-N
Synonyme Oriconazole; R51211
CID PubChem 45039617
Nom IUPAC 1-(butan-2-yl)-4-{4-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-[(1H-1,2,4-triazol-1-yl)methyl]-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-4,5-dihydro-1H-1,2,4-triazol-5-one
SMILES CCC(C)N1N=CN(C1=O)C1=CC=C(C=C1)N1CCN(CC1)C1=CC=C(OC[C@H]2CO[C@@](CN3C=NC=N3)(O2)C2=CC=C(Cl)C=C2Cl)C=C1

Specifications

Nom chimique ou matériau Itraconazole
Type Itraconazole
Forme physique Powder
Point de fusion 166°C
Couleur Blanc
Quantité 5 g
Point d’éclair >110°C (230°F)
Merck Index 14,5245
Informations sur la solubilité Insoluble in water; Solube in chloroform at 50mg/ml; Slightly soluble in ethanol or methanol
Poids de la formule 705.63
Pourcentage de pureté 98%
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RUO – Research Use Only

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