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ITGA6X1A Rabbit anti-Human, Mouse, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Marke: Proteintech 20231-1-AP-150UL
Additional Details : Gewicht : 0.00010kg
Beschreibung
E3 ubiquitin-protein ligase that mediates the ubiquitination of p53/TP53 in the late response to DNA damage, and acts as a positive regulator of p53/TP53 stability, thereby regulating the G1/S DNA damage checkpoint. May act by catalyzing the formation of short polyubiquitin chains on p53/TP53 that are not targeted to the proteasome. In response to ionizing radiation, interacts with MDM2 and enhances p53/TP53 ubiquitination, possibly by restricting MDM2 from extending polyubiquitin chains on ubiquitinated p53/TP53. Plays a role in RPA-mediated DNA damage signaling and repair.Spezifikation
| ITGA6X1A | |
| Polyclonal | |
| Unconjugated | |
| ITGA6 | |
| CD49f, Integrin alpha 6, integrin, alpha 6, ITGA6, ITGA6B, VLA 6 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 16403, 3655 | |
| -20°C | |
| Liquid |
| Western Blot | |
| 0.17 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| P23229, Q61739 | |
| Itga6 | |
| Peptide | |
| 150 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |