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Invitrogen™ Integrin beta 7 Chimeric Recombinant Rabbit Monoclonal Antibody (FIB504)
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Rabbit Recombinant Monoclonal Antibody

Marke:  Invitrogen™ MA548013

Artikelnummer. 17911161

  • 520.00 CHF / 200 Mikrogramm

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Description

Description

Specificity: FIB504 recognizes an epitope on intergin beta-7 subunit that overlaps completely with the epitope defined by Fib27 and Fib30, and also partially with the epitope defined by FIB21 and FIB22.

Integrin beta 7 associates with integrin alpha 4 (CD49d) to form the alpha 4 beta 7 integrin LPAM-1, expressed on intraepithelial lymphocytes. It also associates with alpha E (CD103) to form the alpha E beta 7 integrin HML-1, expressed on T cells adjacent to mucosal epithelium and intraepithelial lymphocytes. Ligands for LPAM-1 include VCAM-1 (CD106), MAdCAM-1 and fibronectin, while the ligand of HML-1 is E-cadherin (CD324). Integrin beta 7 plays an important role in the adhesion of leukocytes to endothelial cells promoting the transmigration of leukocytes to extravascular spaces during the inflammatory response.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Integrin beta 7 Chimeric
Recombinant Monoclonal
1 mg/mL
PBS with 0.02% ProClin 300
P26010, P26011
ITGB7
FIB504 was prepared by immunizing rats with TK1 cells.
200 μg
Primary
Human, Mouse
Antibody
IgG κ
Flow Cytometry, Inhibition Assays, Immunocytochemistry
FIB504
Unconjugated
ITGB7
Gut homing receptor beta subunit; integrin beta 7; integrin beta 7 subunit; integrin beta-7; Integrin beta-P; integrin subunit beta 7; integrin, beta 7; ITGB7; Ly69; M290 IEL antigen
Rabbit
Protein A
RUO
16421, 3695
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
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