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IL-10 Monoclonal Antibody (JES3-9D7), PE, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

143.00 CHF - 355.00 CHF

Spezifikation

Antigen IL-10
Klon JES3-9D7
Anwendungen Flow Cytometry
Klassifikation Monoclonal
Konjugat PE
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Produkte 3
Produktcode Marke Menge Preis Menge & Verfügbarkeit  
Produktcode Marke Menge Preis Menge & Verfügbarkeit  
15269289
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Affymetrix eBioscience
12-7108-81
50 μg
203.00 CHF
50 Mikrogramm
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Verfügbar ab: 09-04-2024
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15279289
Unterlagen ansehen Aktionsdetails
Affymetrix eBioscience
12-7108-82
100 μg
355.00 CHF
100 Mikrogramm
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15547096
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Affymetrix eBioscience
12-7108-41
25 Tests
143.00 CHF
25 Tests
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Beschreibung

Beschreibung

Description: The JES3-9D7 monoclonal antibody reacts with human interleukin-10 (IL-10). Applications Reported: JES3-9D7 has been reported for use in intracellular staining and flow cytometric analysis. Applications Tested: This JES3-9D7 antibody is offered in 2 formats: - μg size: has been tested by intracellular staining and flow cytometric analysis of human activated cells. This can be used at less than or equal to 0.25 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. - test size: has been pre-titrated and tested by intracellular staining and flow cytometric analysis of human activated cells. This can be used at 5 μL (0.125 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser. Filtration: 0.2 μm post-manufacturing filtered.

IL-10 encodes a protein that acts as a cytokine and is primarily produced by monocytes, with some production by lymphocytes. This cytokine has various effects on immunoregulation and inflammation, including down-regulating the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. Additionally, IL-10 can block NF-kappa B activity and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice have suggested that this cytokine is an essential immunoregulator in the intestinal tract. Mutations in this gene have been associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis. Diseases associated with IL10 include Graft-Versus-Host Disease and Human Immunodeficiency Virus Type 1.
Spezifikation

Spezifikation

IL-10
Flow Cytometry
PE
Rat
Human
CSIF; cytokine; Cytokine synthesis inhibitory factor; GVHDS; H-IL-10; il 10; IL10; IL-10; IL-10 precursor; IL10A; IL10X; ILN; Interleukin; interleukin 10; Interleukin10; interleukin-10; MGC126450; MGC126451; RP11-262N9.1; T-cell growth inhibitory factor; TGIF
IL10
Primary
4° C, store in dark, DO NOT FREEZE!
IL10
JES3-9D7
Monoclonal
Liquid
RUO
P22301
3586
IgG1 κ
Affinity chromatography
Antibody
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Product Certifications

For Research Use Only.