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IKBKB Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marke:  Proteintech 20979-1-AP-150UL

Additional Details : Gewicht : 0.00010kg

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Artikelnummer. 16840565

  • 351.68 CHF / 150 Mikroliter

Verfügbar ab: 28-06-2022
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Beschreibung

Beschreibung

The antibody is specific to IKBKB.

Inhibitor of nuclear factor kappa-B kinase subunit beta (IKK beta) is a serine kinase that plays an essential role in the NF-kaapa-B signaling pathway which is activated by mulitple stimuli such as inflammatory cytokines, bacterial, or viral products, DNA damages, or other cellular stresses. IKK beta acts as part of the canonical IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B on 2 critical serine residues. These modifications allow polyubiquitination of the inhibitors and subsequent degradation by the proteasome. In turn, free NF-kappa-B is translocated into the nucleus and activates the transcription of hundreds of genes involved in immune response, growth control, or protection against apoptosis. Mutations affecting the IKK beta gene can result in Immunodeficiency 15 (IMD15).
Spezifikation

Spezifikation

IKBKB
Polyclonal
Unconjugated
IKBKB
I kappa B kinase 2, I kappa B kinase beta, IKBKB, IKK B, IKK beta, IKK2, IKKB, IkappaB, NFKBIKB
Rabbit
Antigen Affinity Chromatography
RUO
16150, 3551
Antibody
IgG
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
0.4 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
O14920, O88351
IKBKB
Peptide
150 μL
Primary
Human, Mouse
Liquid
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation
Zertifikate
Sonderangebote

Sonderangebote