Learn More
ICAM-3 Monoclonal Antibody (MEM-04), Invitrogen™
Mouse Monoclonal Antibody
Marke: Invitrogen MA119030
Additional Details : Gewicht : 0.01000kg
Beschreibung
Low endotoxin azide free phosphate buffered saline (PBS) solution, 0.2 μm filter sterilized. Endotoxin level is less than 0.01 EU/μg of the protein, as determined by the LAL test. Functional Application: Blocking.
CD50 (intracellular adhesion molecule 3, ICAM-3) is a transmembrane glycoprotein expressed by leukocytes, that serves as a counter-receptor for the lymphocyte function-associated antigen (LFA)-1 integrin. Besides functioning as an adhesive molecule that mediates e.g. the contact between T cells and antigen presenting cells, ICAM-3 regulates affinity of LFA-1 for ICAM-1 and induces T cell activation and proliferation. ICAM-3 plays an essential role in the initiation of the immune response both on T cells and antigen presenting cells and interacts also with CD209 (dendritic cell-specific ICAM-3-grabbing nonintegrin, DC-SIGN), a C-type lectin of dendritic cells and macrophages; this process is involved in dialogue between dendritic cells and granulocytes.Spezifikation
ICAM-3 | |
Monoclonal | |
1 mg/mL | |
PBS with no preservative; pH 7.4 | |
P32942 | |
ICAM3 | |
Leukocytes from a patient suffering from LGL type leukemia. | |
100 μg | |
Primary | |
Human | |
Antibody | |
IgG2b κ |
Flow Cytometry, Functional Assay, Immunohistochemistry (Paraffin) | |
MEM-04 | |
Unconjugated | |
ICAM3 | |
CD50; CDw50; ICAM3; ICAM-3; ICAM-R; Intercellular adhesion molecule 3; intercellular adhesion molecule-3 | |
Mouse | |
Protein A | |
RUO | |
3385 | |
4° C, do not freeze | |
Liquid |