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Hypericin, 98%

Artikelnummer. 11466440
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Artikelnummer. 11466440 Lieferant Thermo Scientific Alfa Aesar Lieferanten-Nr. H26425.MC
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Beschreibung

Hypericin, CAS # 548-04-9, is an anthraquinone derivative that shows antidepressant, antiviral, antineoplastic, and immunostimulant activities. | CAS: 548-04-9 | C30H16O8 | 504.45 g/mol

Inhibitor of protein kinase C; induces photosynthesized apoptosisHypercin acts as an antibiotic and antiviral. It is involved in the inhibition of enzyme dopamine beta-hydroxylase action. It also exhibits an anti-HIV and anticancer drug. Further, it is useful in photodynamic therapy. In addition to this, it serves as an inhibitor of protein kinase C which induces photosynthesized apoptosis.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

  • Hypericin is an anthraquinone derivative found in the yellow flower of Hypericum perforatum (also known as St. John's wort)
  • This compound has the ability to inhibit protein kinase C, inducing photosynthesized apoptosis

Application

  • It shows antibiotic and antiviral activities
  • The antidepressant activity of this compound could be related to its ability to inhibit the neuronal uptake of serotonin, norepinephrine, dopamine, gamma-aminobutyric acid (GABA), and L-glutamate
  • Since this compound is able to inhibit the assembly and shedding of virus particles in infected cells, hypericin may also prevent the replication of encapsulated viruses
  • It has been described that this compound can also exhibit anti-HIV and anticancer activities
  • Hypericin also displays an effective phototoxic activity and is able to trigger apoptotic pathways, resulting in the formation of reactive oxygen species
TRUSTED_SUSTAINABILITY

Chemische Identifikatoren

CAS 548-04-9
Summenformel C30H16O8
Molekulargewicht (g/mol) 504.45
MDL-Nummer MFCD00016683
InChI-Schlüssel BTXNYTINYBABQR-UHFFFAOYSA-N
Synonym hypericin, hypericum red, hipericina, hypericine, hyperizin, cyclosan, 1,3,4,6,8,13-hexahydroxy-10,11-dimethylphenanthro 1,10,9,8-opqra perylene-7,14-dione, cyclo-werol, hypericum extract, vimrxyn
PubChem CID 5281051
ChEBI CHEBI:5835
SMILES CC1=CC(=C2C3=C1C4=C5C(=C(C=C4C)O)C(=O)C6=C(C=C(C7=C6C5=C3C8=C7C(=CC(=C8C2=O)O)O)O)O)O

Specifications

Chemischer Name oder Material Hypericin
Schmelzpunkt ∼320°C (decomposition)
Menge 100 mg
Beilstein 1917913
Empfindlichkeit Lichtempfindlich
Merck Index 14,4863
Löslichkeitsinformationen Soluble in ethanol,dimethyl sulfoxide,methanol,acetone,ethylmethylketone,pyridine and sodium hydroxide. Insoluble in water.
Formelmasse 504.44
Reinheit (%) 98%

RUO – Research Use Only

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