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Proteintech HumanKine™ recombinant human IL-12 beta protein
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Menge:
10 μg
100 μg
1000 μg
Packungsgröße:
10 Mikrogramm
100 Mikrogramm
1000 Mikrogramm
Beschreibung
IL-12p40, also known as IL-12B, is a subunit of both the IL-12 and IL-23 cytokines. It is not thought to be bioactive on its own, but it has been shown to regulate IL-12 activity in antagonistic manner by competitively binding with the IL-12 receptor. IL-12p40 also functions as a chemoattractant molecule for macrophage infiltration into tumor sites. There has additionally been evidence to suggest that IL-12p40 mediates a protective immune response against mycobacterial infection by serving as a necessary component for granuloma formation and promoting Th1 effector cell functions (PMID: 17126601, 10453037, 11739515).
Spezifikation
Spezifikation
| Zugriffsnummer | P29460 |
| Zusammensetzung | 1 x PBS pH 7.4 |
| Gen-ID (Entrez) | 3593 |
| Molekulargewicht | 37-50 kDa |
| Menge | 10 μg |
| Quelle | HEK293 |
| Lagerungsbedingungen | Lyophilized product should be stored at -20°C to -80°C until expiry date and (at Room Temperature for 2 weeks.) |
| Endotoxin-Konzentration | <0.1 EU/μg |
| Spezifische Reaktivität | Human |
| Rekombinant | Recombinant |
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