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ACROBiosystems Human TrkB / NTRK2 Protein, His Tag

Marke:  ACROBiosystems NT2-H5228-100UG

Additional Details : Gewicht : 0.00001kg

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Artikelnummer. 15827377

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Beschreibung

Beschreibung

Neurotrophic tyrosine kinase receptor type 2 (NTRK2) is also known as BDNF/NT-3 growth factors receptor, Tropomyosin-related kinase B (TRKB) and TrkB tyrosine kinase, which belongs to the protein kinase superfamily or Tyr protein kinase family. Insulin receptor subfamily. NTRK2 / TrkB contains two Ig-like C2-type (immunoglobulin-like) domains, two LRR (leucine-rich) repeats, one LRRCT domain, one LRRNT domain, one protein kinase domain. NTRK2 / Trk-B is expressed in the central and peripheral nervous system. The catalytic activity of NTRK2 is "e;ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate"e;. NTRK2 / TrkB involved in the development and the maturation of the central and the peripheral nervous systems through regulation of neuron survival, proliferation, migration, differentiation, and synapse formation and plasticity.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 45.2 kDa. The protein migrates as 60-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spezifikation

Spezifikation

AAH31835
HEK293
Human
45.2 kDa
100 µg
Cys 32 - His 430
NTRK2,TRKB,GP145-TrkB
Unconjugated
PBS, pH7.4
Less than 1.0 EU / µg by the LAL method.
Bio-Markers and CD Antigens
Powder
>95% as determined by SDS-PAGE
Human TrkB, His Tag (NT2-H5228) is expressed from human 293 cells (HEK293). It contains AA Cys 32 - His 430 (Accession # AAH31835).
-20°C
TrkB
His Tag
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation