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ACROBiosystems Human TNFR1 / CD120a / TNFRSF1A Protein, Fc Tag
315.25 CHF - 2244.59 CHF
Spezifikation
| Zugriffsnummer | NP_001056 |
|---|---|
| Molekulargewicht | 47.9 kDa |
| Quelle | Human TNFR1, Fc Tag (TN1-H5251) is expressed from human 293 cells (HEK293). It contains AA Ile 22 - Thr 211 (Accession # NP_001056). |
| Immunogen | Ile 22 - Thr 211 |
| Lagerungsbedingungen | -20°C |
| Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
|---|---|---|---|---|---|---|---|---|---|
| Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
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15827807
|
ACROBiosystems
TN1-H5251-1MG |
1 mg |
2244.59 CHF
1 Milligramm |
Verfügbar ab: 16-05-2024
Loggen Sie sich ein, um den Lagerbestand zu sehen |
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|
15817807
|
ACROBiosystems
TN1-H5251-100UG |
100 μg |
315.25 CHF
100 Mikrogramm |
Verfügbar ab: 16-05-2024
Loggen Sie sich ein, um den Lagerbestand zu sehen |
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Beschreibung
Tumor necrosis factor receptor 1 (TNF-R1) is also known as Tumor necrosis factor receptor superfamily member 1A (TNFRSF1A), TNFAR, CD antigen CD120a, which belongs to the tumor necrosis factor receptor superfamily. TNF-R1 contains one death domain and four TNFR-Cys repeats. TNF-R1 is the receptor of TNFSF2 / TNF-alpha and homotrimeric TNFSF1 / lymphotoxin - alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. TNF-R1 contributes to the induction of non - cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase. Defects in TNFRSF1A are the cause of familial hibernian fever (FHF).
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 47.9 kDa. The protein migrates as 58-66 kDa under reducing (R) condition (SDS-PAGE) due to different glycosylation.Spezifikation
| NP_001056 | |
| Human TNFR1, Fc Tag (TN1-H5251) is expressed from human 293 cells (HEK293). It contains AA Ile 22 - Thr 211 (Accession # NP_001056). | |
| -20°C | |
| TNFR1 | |
| Human | |
| Tris with Glycine, Arginine and NaCl, pH7.5 | |
| HEK293 | |
| Bio-Markers and CD Antigens |
| 47.9 kDa | |
| Ile 22 - Thr 211 | |
| TNFR1,CD120a,TNFRSF1A,FPF,TBP1,TNF-R,TNF-R-I,TNF-R55,TNFAR,TNFR55,TNFR60,p55,p60 | |
| Unconjugated | |
| Fc Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >98% as determined by SDS-PAGE |