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ACROBiosystems Human TNF-alpha Protein, His Tag (active trimer)

MALS verified

Marke:  ACROBiosystems TNA-H5228-100UG

Additional Details : Gewicht : 0.00001kg

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Artikelnummer. 15827837

  • 333.92 CHF / 100 Mikrogramm


Verfügbar ab
27-05-2021
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Beschreibung

Beschreibung

Tumor necrosis factor alpha (TNFα) is a cytokine produced primarily by monocytes and macrophages. It is found in synovial cells and macrophages in the tissues.The primary role of TNFα is in the regulation of immune cells. TNFα is able to induce apoptotic cell death, to induce inflammation, and to inhibit tumorigenesis and viral replication. Dysregulation of TNFα production has been implicated in a variety of human diseases, including major depression, Alzheimer's disease and cancer. Recombinant TNFα is used as an immunostimulant under the INN tasonermin. TNFα can be produced ectopically in the setting of malignancy and parallels parathyroid hormone both in causing secondary hypercalcemia and in the cancers with which excessive production is associated.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 18.3 kDa. The protein migrates as 18.2 kDa under reducing (R) condition (SDS-PAGE).
Spezifikation

Spezifikation

NP_000585.2
HEK293
Human
18.3 kDa
100 µg
Val 77 - Leu 233
DIF,TNF-alpha,TNFA,TNFSF2,cachexin,cachectin,TNFα
Unconjugated
PBS, pH7.4
Less than 1.0 EU / µg by the LAL method.
Cytokines and Growth Factors
Powder
>95% as determined by SDS-PAGE
Human TNF-alpha, His Tag (active trimer) (MALS verified) (TNA-H5228) is expressed from human 293 cells (HEK293). It contains AA Val 77 - Leu 233 (Accession # NP_000585.2).
-20°C
TNF-alpha
His Tag
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation