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ACROBiosystems Human Stathmin 1 / STMN1 Protein, His Tag
Marke: ACROBiosystems ST1-H5149-100UG
Additional Details : Gewicht : 0.00001kg
Beschreibung
Stathmin (STMN1), a member of the stathmin family, is also known as Leukemia-associated phosphoprotein p18, Oncoprotein 18 (Op18), Phosphoprotein p19 (pp19), Protein Pr22 and pp17, which contains one SLD (stathmin-like) domain. The function of STMN1 as an important regulatory protein of microtubule dynamics has been well-characterized. Stathmin (STMN1) interacts with two molecules of dimeric α,β-tubulin to form a tight ternary complex called the T2S complex.One mole of STMN1 binds to two moles of tubulin dimers through the stathmin-like domain (SLD).When STMN1 sequesters tubulin into the T2S complex, tubulin becomes non-polymerizable. Without tubulin polymerization, there is no microtubule assembly.STMN1 also promotes microtubule disassembly by acting directly on the microtubule ends.
This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 18.1 kDa. The protein migrates as 18 kDa under reducing (R) condition (SDS-PAGE).Spezifikation
| NP_981946 | |
| 100 μg | |
| Ala 2 - Asp 149 | |
| STMN1,Stathmin,C1orf215,LAP18,OP18 | |
| Unconjugated | |
| His Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >92% as determined by SDS-PAGE |
| 18.1 kDa | |
| Human Stathmin 1, His Tag (ST1-H5149) is expressed from E.coli cells. It contains AA Ala 2 - Asp 149 (Accession # NP_981946). | |
| -20°C | |
| Stathmin 1 | |
| Human | |
| PBS, pH7.4 | |
| E.coli | |
| Other Recombinant Proteins |