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ACROBiosystems Human Stathmin 1 / STMN1 Protein, His Tag

Marke:  ACROBiosystems ST1-H5149-1MG

Additional Details : Gewicht : 0.00001kg

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Artikelnummer. 15827727

  • 1128.43 CHF / 1 Milligramm


Verfügbar ab
28-05-2021
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Beschreibung

Beschreibung

Stathmin (STMN1), a member of the stathmin family, is also known as Leukemia-associated phosphoprotein p18, Oncoprotein 18 (Op18), Phosphoprotein p19 (pp19), Protein Pr22 and pp17, which contains one SLD (stathmin-like) domain. The function of STMN1 as an important regulatory protein of microtubule dynamics has been well-characterized. Stathmin (STMN1) interacts with two molecules of dimeric α,β-tubulin to form a tight ternary complex called the T2S complex.One mole of STMN1 binds to two moles of tubulin dimers through the stathmin-like domain (SLD).When STMN1 sequesters tubulin into the T2S complex, tubulin becomes non-polymerizable. Without tubulin polymerization, there is no microtubule assembly.STMN1 also promotes microtubule disassembly by acting directly on the microtubule ends.

This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 18.1 kDa. The protein migrates as 18 kDa under reducing (R) condition (SDS-PAGE).
Spezifikation

Spezifikation

NP_981946
E.coli
Human
18.1 kDa
1 mg
Ala 2 - Asp 149
STMN1,Stathmin,C1orf215,LAP18,OP18
Unconjugated
PBS, pH7.4
Less than 1.0 EU / µg by the LAL method.
Other Recombinant Proteins
Powder
>92% as determined by SDS-PAGE
Human Stathmin 1, His Tag (ST1-H5149) is expressed from E.coli cells. It contains AA Ala 2 - Asp 149 (Accession # NP_981946).
-20°C
Stathmin 1
His Tag
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation