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ACROBiosystems Human Siglec-2 / CD22 (176-687) Protein, His Tag

Marke:  ACROBiosystems SI2-H5228-100UG

Additional Details : Gewicht : 0.00001kg

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Artikelnummer. 15827687

  • 333.92 CHF / 100 Mikrogramm


Verfügbar ab
28-05-2021
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Beschreibung

Beschreibung

B-cell receptor CD22 is also known as Sialic acid-binding Ig-like lectin 2 (Siglec-2), B-lymphocyte cell adhesion molecule (BL-CAM), T-cell surface antigen Leu-14, which belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. CD22 mediates B-cell B-cell interactions, and may be involved in the localization of B-cells in lymphoid tissues. Siglec-2 / CD22 binds sialylated glycoproteins, one of which is CD45. Siglec2 / CD22 plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 58.1 kDa. The protein migrates as 90-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spezifikation

Spezifikation

P20273-1
HEK293
Human
58.1 kDa
100 µg
Trp 176 - Arg 687
CD22,SIGLEC2,BL-CAM,SIGLEC-2,Siglec2,SIGLEC2FLJ22814
Unconjugated
PBS, pH7.4
Less than 1.0 EU / µg by the LAL method.
Bio-Markers and CD Antigens
Powder
>95% as determined by SDS-PAGE
Human Siglec-2 (176-687), His Tag (SI2-H5228) is expressed from human 293 cells (HEK293). It contains AA Trp 176 - Arg 687 (Accession # P20273-1).
-20°C
Siglec-2
His Tag
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation