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ACROBiosystems Human ROR1 Protein, Fc Tag
315.25 CHF - 1374.49 CHF
Spezifikation
Zugriffsnummer | NP_005003.2 |
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Molekulargewicht | 68.6 kDa |
Quelle | Human ROR1, Fc Tag (RO1-H5250) is expressed from human 293 cells (HEK293). It contains AA Gln 30 - Glu 403 (Accession # Q01973-1). |
Immunogen | Gln 30 - Glu 403 |
Lagerungsbedingungen | -20°C |
Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
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Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
15827597
|
ACROBiosystems
RO1-H5250-200UG |
200 μg |
315.25 CHF
200 Mikrogramm |
Verfügbar ab: 16-05-2024
Loggen Sie sich ein, um den Lagerbestand zu sehen |
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15817597
|
ACROBiosystems
RO1-H5250-1MG |
1 mg |
1374.49 CHF
1 Milligramm |
Verfügbar ab: 16-05-2024
Loggen Sie sich ein, um den Lagerbestand zu sehen |
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Beschreibung
Tyrosine-protein kinase transmembrane receptor ROR1 is also known as Neurotrophic tyrosine kinase, receptor-related 1 (NTRKR1), which belongs to the protein kinase superfamily or tyr protein kinase family or ROR subfamily. ROR1 contains 1 FZ (frizzled) domain, 1 Ig-like C2-type (immunoglobulin-like) domain, 1 kringle domain, 1 protein kinase domain. ROR1 is expressed at high levels during early embryonic development. The expression levels drop strongly around day 16 and there are only very low levels in adult tissues. Isoform Short is strongly expressed in fetal and adult CNS and in a variety of human cancers, including those originating from CNS or PNS neuroectoderm. ROR1 could interact with casein kinase 1 epsilon (CK1ε) to activate phosphoinositide 3-kinase-mediated AKT phosphorylation and cAMP-response-element-binding protein (CREB), which was associated with enhanced tumor-cell growth.
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 68.6 kDa. The protein migrates as 79-95 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spezifikation
NP_005003.2 | |
Human ROR1, Fc Tag (RO1-H5250) is expressed from human 293 cells (HEK293). It contains AA Gln 30 - Glu 403 (Accession # Q01973-1). | |
-20°C | |
ROR1 | |
Human | |
Tris with Glycine, Arginine and NaCl, pH7.5 | |
HEK293 | |
Bio-Markers and CD Antigens |
68.6 kDa | |
Gln 30 - Glu 403 | |
ROR1,NTRKR1 | |
Unconjugated | |
Fc Tag | |
Less than 1.0 EU / μg by the LAL method. | |
Powder | |
>90% as determined by SDS-PAGE |