Learn More
ACROBiosystems Human Prolactin R / PRLR Protein, His Tag
378.31 CHF - 2774.20 CHF
Spezifikation
Zugriffsnummer | NP_000940.1 |
---|---|
Molekulargewicht | 26.3 kDa |
Quelle | Human Prolactin R, His Tag (PRR-H52Ha) is expressed from human 293 cells (HEK293). It contains AA Gln 25 - Asp 234 (Accession # P16471-1). |
Immunogen | Gln 25 - Asp 234 |
Lagerungsbedingungen | -20°C |
Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
---|---|---|---|---|---|---|---|---|---|
Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
15837557
|
ACROBiosystems
PRR-H52HA-1MG |
1 mg |
2774.20 CHF
1 Milligramm |
Verfügbar ab: 07-05-2024
Loggen Sie sich ein, um den Lagerbestand zu sehen |
|||||
15827557
|
ACROBiosystems
PRR-H52HA-100UG |
100 μg |
378.31 CHF
100 Mikrogramm |
Verfügbar ab: 07-05-2024
Loggen Sie sich ein, um den Lagerbestand zu sehen |
|||||
Beschreibung
As a transmembrane receptor, the prolactin receptor (PRL-R) interacts with prolactin. In addition, the PRL-R also binds and is activated by growth hormone (GH) and human placental lactogen (hPL). Preclinical investigations, epidemiological studies and analyses of tissue specimens from patients strongly support the contribution of prolactin receptor (PRLR) signaling to breast and prostate tumorigenesis and cancer progression. Moreover, The PRLR has been found to be essential for lobuloalveolar maturation of the mammary glands during pregnancy, as evidenced by the fact that PRLR knockout mice show severely impaired development of lobuloalveolar structures.
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 26.3 kDa. The protein migrates as 35-40 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spezifikation
NP_000940.1 | |
Human Prolactin R, His Tag (PRR-H52Ha) is expressed from human 293 cells (HEK293). It contains AA Gln 25 - Asp 234 (Accession # P16471-1). | |
-20°C | |
Prolactin R | |
Human | |
50 mM Tris, 150 mM NaCl, pH7.5 | |
HEK293 | |
Cytokines and Growth Factors |
26.3 kDa | |
Gln 25 - Asp 234 | |
Prolactin R,PRLR,PRL-R | |
Unconjugated | |
His Tag | |
Less than 1.0 EU / μg by the LAL method. | |
Powder | |
>95% as determined by SDS-PAGE |