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ACROBiosystems Human Prolactin R / PRLR Protein, His Tag

378.31 CHF - 2774.20 CHF

Spezifikation

Zugriffsnummer NP_000940.1
Molekulargewicht 26.3 kDa
Quelle Human Prolactin R, His Tag (PRR-H52Ha) is expressed from human 293 cells (HEK293). It contains AA Gln 25 - Asp 234 (Accession # P16471-1).
Immunogen Gln 25 - Asp 234
Lagerungsbedingungen -20°C
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Produkte 2
Produktcode Marke Menge Preis Menge & Verfügbarkeit  
Produktcode Marke Menge Preis Menge & Verfügbarkeit  
15837557
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ACROBiosystems
PRR-H52HA-1MG
1 mg
2774.20 CHF
1 Milligramm
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15827557
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ACROBiosystems
PRR-H52HA-100UG
100 μg
378.31 CHF
100 Mikrogramm
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Verfügbar ab: 07-05-2024
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Beschreibung

Beschreibung

As a transmembrane receptor, the prolactin receptor (PRL-R) interacts with prolactin. In addition, the PRL-R also binds and is activated by growth hormone (GH) and human placental lactogen (hPL). Preclinical investigations, epidemiological studies and analyses of tissue specimens from patients strongly support the contribution of prolactin receptor (PRLR) signaling to breast and prostate tumorigenesis and cancer progression. Moreover, The PRLR has been found to be essential for lobuloalveolar maturation of the mammary glands during pregnancy, as evidenced by the fact that PRLR knockout mice show severely impaired development of lobuloalveolar structures.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 26.3 kDa. The protein migrates as 35-40 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spezifikation

Spezifikation

NP_000940.1
Human Prolactin R, His Tag (PRR-H52Ha) is expressed from human 293 cells (HEK293). It contains AA Gln 25 - Asp 234 (Accession # P16471-1).
-20°C
Prolactin R
Human
50 mM Tris, 150 mM NaCl, pH7.5
HEK293
Cytokines and Growth Factors
26.3 kDa
Gln 25 - Asp 234
Prolactin R,PRLR,PRL-R
Unconjugated
His Tag
Less than 1.0 EU / μg by the LAL method.
Powder
>95% as determined by SDS-PAGE
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

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