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ACROBiosystems Human Prolactin R / PRLR Protein, His Tag

Marke:  ACROBiosystems PRR-H52HA-100UG

Additional Details : Gewicht : 0.00001kg

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Artikelnummer. 15827557

  • 345.44 CHF / 100 Mikrogramm


Verfügbar ab
28-05-2021
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Beschreibung

Beschreibung

As a transmembrane receptor, the prolactin receptor (PRL-R) interacts with prolactin. In addition, the PRL-R also binds and is activated by growth hormone (GH) and human placental lactogen (hPL). Preclinical investigations, epidemiological studies and analyses of tissue specimens from patients strongly support the contribution of prolactin receptor (PRLR) signaling to breast and prostate tumorigenesis and cancer progression. Moreover, The PRLR has been found to be essential for lobuloalveolar maturation of the mammary glands during pregnancy, as evidenced by the fact that PRLR knockout mice show severely impaired development of lobuloalveolar structures.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 26.3 kDa. The protein migrates as 35-40 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spezifikation

Spezifikation

NP_000940.1
HEK293
Human
26.3 kDa
100 µg
Gln 25 - Asp 234
Prolactin R,PRLR,PRL-R
Unconjugated
50 mM Tris, 150 mM NaCl, pH7.5
Less than 1.0 EU / µg by the LAL method.
Cytokines and Growth Factors
Powder
>95% as determined by SDS-PAGE
Human Prolactin R, His Tag (PRR-H52Ha) is expressed from human 293 cells (HEK293). It contains AA Gln 25 - Asp 234 (Accession # P16471-1).
-20°C
Prolactin R
His Tag
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation