missing translation for 'onlineSavingsMsg'
Learn More

ACROBiosystems Human PLAU / uPA Protein, His Tag

Marke:  ACROBiosystems PLU-H5229-50UG

Additional Details : Gewicht : 0.00001kg

 Lernen Sie weitere Varianten dieses

Artikelnummer. 15817547

  • 356.95 CHF / 50 Mikrogramm


Verfügbar ab
28-05-2021
Zum Warenkorb hinzufügen

Beschreibung

Beschreibung

Urokinase - type plasminogen activator is also known as PLAU and UPA, a serine protease with an extremely limited substrate specificity, cleaving the sequence Cys – Pro – Gly - Arg560 - Val561 – Val – Gly – Gly – Cys in plasminogen to form plasmin. uPA is a potent marker of invasion and metastasis in a variety of human cancers associated with breast, stomach, colon, bladder, ovary, brain and endometrium.uPA and its receptor (uPAR) have been implicated in a broad spectrum of pathophysiological processes, including fibrinolysis, proteolysis, inflammation, atherogenesis and plaque destabilization, all of which are involved in the pathogenesis of MI (myocardial infarction).

Human PLAU, His Tag is fused with a polyhistidine tag at the C-terminus, and has a calculated MW of 47.2 kDa. The protein migrates as 45-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Please note that the protein is not a
Spezifikation

Spezifikation

NP_002649.1
HEK293
Human
47.2 kDa
50 µg
Ser 21 - Leu 431
Urokinase,PLAU,ATF,UPA,URK,u-PA,BDPLT5,QPD
Unconjugated
50 mM Sodium Acetate, 100 mM NaCl, pH5.0
Less than 1.0 EU / µg by the LAL method.
Enzymes
Powder
>92% as determined by SDS-PAGE
Human PLAU, His Tag (PLU-H5229) is expressed from human 293 cells (HEK293). It contains AA Ser 21 - Leu 431 (Accession # NP_002649.1).
-20°C
PLAU
His Tag
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation