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Gibco™ Human OCT1 (G) SLC Transporter Cells

Codice prodotto. 17136632 Sfoglia Tutto Gibco Prodotti
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Quantità:
8–10M cells
Dimensione della confezione:
Pezzo
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Codice prodotto. Quantità Dimensione della confezione
17136632 8–10M cells Pezzo
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Codice prodotto. 17136632 Fornitore Gibco™ N. del fornitore GM1108G
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HEK293 cells that transiently overexpress the OCT1 solute carrier (SLC) transport protein

  • TRANSiPORT Human OCT1 (G) SLC Transporter Cells are HEK293 cells that transiently overexpress the OCT1 solute carrier (SLC) transport protein. Solute carriers are a super-family of membrane transporters that can affect pharmacokinetics and drug exposure by governing the transport of solutes in and out of cells. The OCT1 SLC transporter protein is found in hepatocytes.
  • Assess potential for transporter-mediated drug metabolism
  • Easy to use format
  • Obtain high quality results with a large signal-to-noise ratio
  • Cell-based assays can be performed using radioisotope-labeled compounds, fluorescence-labeled compounds, or non-labeled compounds. The amount of substrate transported into the cells can be measured directly using a liquid scintillation counter, fluorescence plate reader, or LC-MS/MS, thereby allowing direct evaluation of SLC transporter activity.
  • Mock HEK293 cells (Cat. No. GM1101G) that do not overexpress the SLC transporter are available for use as a negative experimental control. Some compounds may demonstrate high background levels of transport due to the presence of endogenous transporters or non-specific binding.
  • The convenient product format enables data generation in 2 days from thawing of the cells to final results.
TRUSTED_SUSTAINABILITY

Specifica

Content And Storage Store in liquid nitrogen vapor phase.
Linea cellulare 293 (HEK)
Culture Type Mammalian Cell Culture
Specie Human
N. di celle 8-10 x 106
Product Type SLC Transporter Cell
Quantità 8–10M cells
Titolo del prodotto
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