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ACROBiosystems Human Neuropilin-1 / NRP1 / CD304 Protein, Fc Tag
315.25 CHF - 2244.59 CHF
Specifications
| Zugriffsnummer | AAH07533 |
|---|---|
| Molekulargewicht | 96.5 kDa |
| Quelle | Human NRP1, Fc Tag (NR1-H5252) is expressed from human 293 cells (HEK293). It contains AA Phe 22 - Lys 644 (Accession # AAH07533). |
| Immunogen | Phe 22 - Lys 644 |
| Lagerungsbedingungen | -20°C |
| Product Code | Brand | Menge | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Menge | Price | Quantity & Availability | |||||
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15837367
|
ACROBiosystems
NR1-H5252-50UG |
50 μg |
315.25 CHF
50 Mikrogramm |
Verfügbar ab: 02-05-2024
Loggen Sie sich ein, um den Lagerbestand zu sehen |
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|
15827367
|
ACROBiosystems
NR1-H5252-1MG |
1 mg |
2244.59 CHF
1 Milligramm |
Verfügbar ab: 02-05-2024
Loggen Sie sich ein, um den Lagerbestand zu sehen |
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Description
Neuropilin-1 (NRP1) is also known as Vascular endothelial cell growth factor 165 receptor (VEGF165R), CD antigen CD304, which belongs to the neuropilin family. The membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, The PLGF-2 isoform of PGF, The VEGF-165 isoform of VEGF and VEGF-B. Coexpression with KDR results in increased VEGF-165 binding to KDR as well as increased chemotaxis. It may regulate VEGF-induced angiogenesis. The soluble isoform 2 binds VEGF-165 and appears to inhibit its binding to cells.
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 96.5 kDa. The protein migrates as 105-130 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Specifications
| AAH07533 | |
| Human NRP1, Fc Tag (NR1-H5252) is expressed from human 293 cells (HEK293). It contains AA Phe 22 - Lys 644 (Accession # AAH07533). | |
| -20°C | |
| Neuropilin-1 | |
| Human | |
| Tris with Glycine, Arginine and NaCl, pH7.5 | |
| HEK293 | |
| Bio-Markers and CD Antigens |
| 96.5 kDa | |
| Phe 22 - Lys 644 | |
| NRP1,Neuropilin-1,NRP,VEGF165R,CD304 | |
| Unconjugated | |
| Fc Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >90% as determined by SDS-PAGE |