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ACROBiosystems Human Neprilysin / MME / CD10 Protein, Tag Free

500.23 CHF - 3051.42 CHF

Spezifikation

Zugriffsnummer NP_000893.2
Molekulargewicht 80.0 kDa
Quelle Human Neprilysin, Tag Free (MME-H521b) is expressed from human 293 cells (HEK293). It contains AA Tyr 52 - Trp 750 (Accession # NP_000893.2).
Immunogen Tyr 52 - Trp 750
Lagerungsbedingungen -20°C
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Produkte 2
Produktcode Marke Menge Preis Menge & Verfügbarkeit  
Produktcode Marke Menge Preis Menge & Verfügbarkeit  
15807317
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ACROBiosystems
MME-H521B-1MG
1 mg
3051.42 CHF
1 Milligramm
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Verfügbar ab: 10-04-2024
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15817317
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ACROBiosystems
MME-H521B-50UG
50 μg
500.23 CHF
50 Mikrogramm
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Verfügbar ab: 10-04-2024
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Beschreibung

Beschreibung

Cluster of differentiation 10 (CD10) is also known as membrane metallo-endopeptidase, neutral endopeptidase (NEP), Neprilysin, and common acute lymphoblastic leukemia antigen (CALLA), is a 90-110-kDa type II transmembrane glycoprotein normally expressed by a variety of tissues, including epithelial cells of the prostate, kidney, intestine, endometrium, adrenal glands, and lung. This zinc-dependent metalloprotease enzyme cleaves peptide bonds on the amino side of hydrophobic residues and inactivates a variety of physiologically active secreted peptides. CD20 is thought to be the rate-limiting degrading enzyme of amyloid β peptide (Aβ) whose abnormal misfolding and aggregation in neural tissue has been implicated in the development of Alzheimer's disease (AD). CD10 is also identified as the common acute lymphoblastic leukemia antigen (CALLA) present on leukemic cells of pre-B phenotype, and thus serves as the most important biomarker in the diagnosis of human acute lymphocytic leukemia (ALL).

This protein carries no "e;tag"e;. The protein has a calculated MW of 80.0 kDa. The protein migrates as 80-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spezifikation

Spezifikation

NP_000893.2
Human Neprilysin, Tag Free (MME-H521b) is expressed from human 293 cells (HEK293). It contains AA Tyr 52 - Trp 750 (Accession # NP_000893.2).
-20°C
Neprilysin
Human
20 mM Tris, 100 mM NaCl, pH8.0
HEK293
Enzymes
80.0 kDa
Tyr 52 - Trp 750
MME,CALLA,CD10,DKFZp686O16152,MGC126681,MGC126707,NEP,SFE,Neprilysin
Unconjugated
Tag Free
Less than 1.0 EU / μg by the LAL method.
Powder
>95% as determined by SDS-PAGE
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

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