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Gibco™ Human/Mouse/Rat BDNF Recombinant Protein, PeproTech®
E. coli Recombinant Protein
89.25 CHF - 5780.00 CHF
Spezifikation
| Zugriffsnummer | P21237, P23363, P23560 |
|---|---|
| Zur Verwendung mit (Anwendung) | ELISA, Functional Assay, Western Blot |
| Zusammensetzung | protein with no preservative |
| Gen-ID (Entrez) | 12064, 24225, 627 |
| Molekulargewicht | 27 |
| Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
|---|---|---|---|---|---|---|---|---|---|
| Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
|
17874463
|
Gibco™
450-02-100UG |
100 μg |
1156.00 CHF
100 Mikrogramm |
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|
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|
17834733
|
Gibco™
450-02-10UG |
10 μg |
217.00 CHF
10 Mikrogramm |
Lager vorrätigLoggen Sie sich ein, um den Lagerbestand zu sehen
|
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|
17824183
|
Gibco™
450-02-1MG |
1 mg |
5780.00 CHF
1 Milligramm |
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|
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|
17894313
|
Gibco™
450-02-250UG |
250 μg |
2025.00 CHF
250 Mikrogramm |
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|
|||||
|
17854143
|
Gibco™
450-02-2UG |
2 μg |
89.25 CHF
2 Mikrogramm |
Verfügbar ab: 27-05-2024
Loggen Sie sich ein, um den Lagerbestand zu sehen |
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|
17854253
|
Gibco™
450-02-500UG |
500 μg |
3465.00 CHF
500 Mikrogramm |
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|
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|
17874523
|
Gibco™
450-02-50UG |
50 μg |
694.00 CHF
50 Mikrogramm |
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|
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Beschreibung
BDNF (Brain-Derived Neurotrophic Factor) is a member of the neurotrophin family. BDNF is synthesized as pre-proBDNF, followed by cleavage to proBDNF. Although further processing generates the mature, 14 kDa protein, pro-BDNF is biologically active and is secreted in synaptic vesicles along with the mature form. BDNF is widely expressed in the central nervous system and acts in an autocrine and paracrine manner on several classes of neurons. Signaling occurs mainly through the tyrosine kinase receptor TrkB, although binding to the lower-affinity receptor, p75-NTR, has also been demonstrated. BDNF promotes neuronal survival and differentiation and has been shown to play a critical role in memory formation and synaptic regulation. BDNF is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of BDNF is reduced in both Alzheimer's and Huntington disease patients, and may also play a role in the regulation of stress response and in the biology of mood disorders.Spezifikation
| P21237, P23363, P23560 | |
| protein with no preservative | |
| 27 | |
| E. coli | |
| RUO | |
| abrineurin; ANON2; anorexia BDNF; Bdnf; BDNF precursor form; bdnf protein; brain derived neurothrophic factor; brain derived neurotrophic factor; brain-derived neurotrophic factor; BULN2; H-BDNF; neurotrophin; ProBDNF | |
| Human, Mouse, Rat | |
| Recombinant | |
| Lyophilized |
| ELISA, Functional Assay, Western Blot | |
| 12064, 24225, 627 | |
| Human/Mouse/Rat BDNF | |
| -20°C | |
| <1 EU/μg | |
| BDNF | |
| Unconjugated | |
| MHSDPARRGE LSVCDSISEW VTAADKKTAV DMSGGTVTVL EKVPVSKGQL KQYFYETKCN PMGYTKEGCR GIDKRHWNSQ CRTTQSYVRA LTMDSKKRIG WRFIRIDTSC VCTLTIKRGR | |
| ≥ 98% by SDS-PAGE gel and HPLC analyses. |