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Gibco™ Human/Mouse/Rat Activin A Recombinant Protein, PeproTech®

Artikelnummer. 17850193
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Menge:
10 μg
100 μg
2 μg
2 x 500 μg
250 μg
50 μg
500 μg
Packungsgröße:
1 Milligramm
10 Mikrogramm
100 Mikrogramm
2 Mikrogramm
2 Stück
250 Mikrogramm
50 Mikrogramm
500 Mikrogramm
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Artikelnummer. Menge unitSize
17850193 10 μg 10 Mikrogramm
17861533 100 μg 100 Mikrogramm
30087397 2 x 500 μg 2 Stück
17850963 2 x 500 μg 1 Milligramm
17860393 250 μg 250 Mikrogramm
17881533 2 μg 2 Mikrogramm
17890013 500 μg 500 Mikrogramm
17811473 50 μg 50 Mikrogramm
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Artikelnummer. 17850193 Lieferant Gibco™ Lieferanten-Nr. 12014P10UG

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Description

Recombinant Protein

120-14P-1MG will be provided as 2 x 500 μg (120-14P-500UG). Recombinant Human/Murine/Rat Activin A is a 26.0 kDa disulfide-linked homodimer of two betaA chains, each containing 116 amino acid residues. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Activin A mutations are associated with fibrodysplasia ossificans progressive.
TRUSTED_SUSTAINABILITY

Specifications

Zugriffsnummer P08476, P18331, Q04998
Zur Verwendung mit (Anwendung) Control, Bioactivity
Zusammensetzung Protein with no preservative
Gen-ID (Entrez) 16323, 29200, 3624
Molekulargewicht 26 kDa
Name Human/Mouse/Rat Activin A
Reinigungsverfahren Purified
Menge 10 μg
Quelle CHO cells
Lagerungsbedingungen -20°C
Kennzeichnung RUO
Endotoxin-Konzentration <1 EU/μg
Gen-Alias activin A; activin beta-A chain; BMP7; BMP-7; Bone morphogenetic protein 7; EDF; Eptotermin alfa; erythroid differentiation factor; erythroid differentiation protein; follicle-stimulating hormone-releasing protein; FRP; FSH-releasing protein; INHB; Inhba; inhibin B subunit; inhibin beta A chain; inhibin beta A protein; inhibin beta A subunit; inhibin beta-A; inhibin beta-A-subunit; inhibin beta-subunit; inhibin subunit beta A; inhibin, beta A; inhibin, beta A (activin A, activin AB alpha polypeptide); Inhibin, beta-1; OP1; OP-1; Osteogenic protein 1; unnamed protein product
Gebräuchliche Bezeichnung Activin A
Gensymbol Inhba
Biologische Aktivität Determined by its ability to inhibit the proliferation of mouse MPC-11 cells. The expected ED50 is ≤ 2.0 ng/ml, corresponding to a specific activity of ≥ 5 x 10^5 units/mg
Produkttyp Protein
Konjugat Unconjugated
Rekombinant Recombinant
Sequenz GLECDGKVNI CCKKQFFVSF KDIGWNDWII APSGYHANYC EGECPSHIAG TSGSSLSFHS TVINHYRMRG HSPFANLKSC CVPTKLRPMS MLYYDDGQNI IKKDIQNMIV EECGCS
Inhalt und Lagerung -20°C
Aktivität Determined by its ability to inhibit the proliferation of mouse MPC-11 cells. The expected ED50 is ≤ 2.0 ng/ml, corresponding to a specific activity of ≥ 5 x 10^5 units/mg.
Expressionssystem CHO cells
Form Lyophilized
Reinheits- oder Qualitätsgrad ≥ 95% by SDS-PAGE gel and HPLC analyses.
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