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ACROBiosystems Human LILRB4 / CD85k / ILT3 Protein, Mouse IgG2a Fc Tag, low endotoxin

low endotoxin

Marke:  ACROBiosystems CDK-H5259-1MG

Additional Details : Gewicht : 0.00001kg

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Artikelnummer. 15826417

  • auf Anfrage / 1 Milligramm

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Beschreibung

Beschreibung

Leukocyte immunoglobulin-like receptor subfamily B member 4 (LILRB4) is also known as CD85 antigen-like family member K (CD85K), Immunoglobulin-like transcript 3 (ILT-3), Leukocyte immunoglobulin-like receptor 5 (LIR-5), Monocyte inhibitory receptor HM18, which belongs to the leukocyte immunoglobulin-like receptor (LIR) family. LILRB4 / CD85K contains 2 Ig-like C2-type (immunoglobulin-like) domains. CD85K is detected in monocytes, macrophages, dendritic cells, lung, natural killer cells and B-cells. LILRB4 / CD85K is receptor for class I MHC antigens. CD85K recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles, involved in the down-regulation of the immune response and the development of tolerance. LILRB4 interferes with TNFRSF5-signaling and NF-kappa-B up-regulation and inhibits receptor-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.

This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 53.2 kDa. The protein migrates as 60-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spezifikation

Spezifikation

AAH26309.1
HEK293
Human
53.2 kDa
1 mg
Gln 22 - Glu 259
LILRB4,ILT3,LIR5,CD85K,HM18
Unconjugated
50 mM Tris, 100 mM Glycine, pH7.5
Less than 0.1 EU / µg by the LAL method.
Immune Checkpoint Proteins
Powder
>90% as determined by SDS-PAGE
Human LILRB4, Mouse IgG2a Fc Tag, low endotoxin (CDK-H5259) is expressed from human 293 cells (HEK293). It contains AA Gln 22 - Glu 259 (Accession # AAH26309.1).
-20°C
LILRB4
Mouse IgG Fc Tag
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