missing translation for 'onlineSavingsMsg'
Learn More
Learn More
ACROBiosystems Human LILRB4 / CD85k / ILT3 Protein, Fc Tag
SPR verified
auf Anfrage
Spezifikation
| Zugriffsnummer | AAH26309 |
|---|---|
| Molekulargewicht | 52.9 kDa |
| Quelle | Human LILRB4, Fc Tag (SPR verified) (LI4-H5259) is expressed from human 293 cells (HEK293). It contains AA Gln 22 - Glu 259 (Accession # AAH26309). |
| Immunogen | Gln 22 - Glu 259 |
| Lagerungsbedingungen | -20°C |
| Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
|---|---|---|---|---|---|---|---|---|---|
| Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
|
15817267
|
ACROBiosystems
LI4-H5259-50UG |
50 µg |
Dieser Artikel wurde eingestellt und ist leider nicht mehr verfügbar. Sehen Sie sich das Produkt an, um alternative Produktvorschläge zu sehen oder kontaktieren Sie unseren Technischen Support unter 056 618 41 11. |
||||||
|
15807267
|
ACROBiosystems
LI4-H5259-1MG |
1 mg |
Dieser Artikel wurde eingestellt und ist leider nicht mehr verfügbar. Sehen Sie sich das Produkt an, um alternative Produktvorschläge zu sehen oder kontaktieren Sie unseren Technischen Support unter 056 618 41 11. |
||||||
Beschreibung
Leukocyte immunoglobulin-like receptor subfamily B member 4 (LILRB4) is also known as CD85 antigen-like family member K (CD85K), Immunoglobulin-like transcript 3 (ILT-3), Leukocyte immunoglobulin-like receptor 5 (LIR-5), Monocyte inhibitory receptor HM18, which belongs to the leukocyte immunoglobulin-like receptor (LIR) family. LILRB4 / CD85K contains 2 Ig-like C2-type (immunoglobulin-like) domains. CD85K is detected in monocytes, macrophages, dendritic cells, lung, natural killer cells and B-cells. LILRB4 / CD85K is receptor for class I MHC antigens. CD85K recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles, involved in the down-regulation of the immune response and the development of tolerance. LILRB4 interferes with TNFRSF5-signaling and NF-kappa-B up-regulation and inhibits receptor-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 52.9 kDa. The protein migrates as 57-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spezifikation
| AAH26309 | |
| Human LILRB4, Fc Tag (SPR verified) (LI4-H5259) is expressed from human 293 cells (HEK293). It contains AA Gln 22 - Glu 259 (Accession # AAH26309). | |
| -20°C | |
| LILRB4 | |
| Human | |
| 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5 | |
| HEK293 | |
| Immune Checkpoint Proteins |
| 52.9 kDa | |
| Gln 22 - Glu 259 | |
| LILRB4,ILT3,LIR5,CD85K,HM18 | |
| Unconjugated | |
| Fc Tag | |
| Less than 1.0 EU / µg by the LAL method. | |
| Powder | |
| >95% as determined by SDS-PAGE |