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ACROBiosystems Human IL-2 R gamma / CD132 Protein, Fc Tag
340.47 CHF - 2522.00 CHF
Spezifikation
Zugriffsnummer | AAH14972 |
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Molekulargewicht | 53.5 kDa |
Quelle | Human IL-2 R gamma, Fc Tag (ILG-H5256) is expressed from human 293 cells (HEK293). It contains AA Leu 23 - Asn 254 (Accession # AAH14972). |
Immunogen | Leu 23 - Asn 254 |
Lagerungsbedingungen | -20°C |
Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
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Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
15817107
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ACROBiosystems
ILG-H5256-100UG |
100 μg |
340.47 CHF
100 Mikrogramm |
Verfügbar ab: 02-05-2024
Loggen Sie sich ein, um den Lagerbestand zu sehen |
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16447769
|
ACROBiosystems
ILG-H5256-1MG |
1 mg |
2522.00 CHF
1 Milligramm |
Verfügbar ab: 02-05-2024
Loggen Sie sich ein, um den Lagerbestand zu sehen |
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Beschreibung
IL-2R is a heterotrimeric protein binds and responds to the cytokine IL-2. Three distinct chains of IL-2R, termed as α, β and γ, which are non-covalently associated are identified. The α and β chains are involved in binding IL-2, while signal transduction following cytokine interaction is carried out by the γ chain, along with the β subunit. The α chain of the IL-2R can bind to the β chain before receptor interaction with IL-2. The γ chain alone has a very weak affinity for IL-2, but after the ligand is bound to the α/β heterodimer, the γ chain becomes recruited to the complex to form a very stable macromolecular quaternary ligand/receptor complex. Interleukin-2 receptor subunit gamma (IL2RG), also known as cytokine receptor common subunit gamma, CD antigen CD132, gammaC, p64, which belongs to the type I cytokine receptor family or type 5 subfamily. IL2RG is located on the surface of immature blood-forming cells in bone marrow. Defects in IL2RG are the cause of severe combined immunodeficiency X-linked T-cell-negative/B-cell-positive/NK-cell-negative (XSCID).
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 53.5 kDa. The protein migrates as 75-96 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spezifikation
AAH14972 | |
Human IL-2 R gamma, Fc Tag (ILG-H5256) is expressed from human 293 cells (HEK293). It contains AA Leu 23 - Asn 254 (Accession # AAH14972). | |
-20°C | |
IL-2 R gamma | |
Human | |
Tris with Glycine, Arginine and NaCl, pH7.5 | |
HEK293 | |
Bio-Markers and CD Antigens |
53.5 kDa | |
Leu 23 - Asn 254 | |
IL2RG,CD132,CIDX,IMD4,P64,SCIDX,SCIDX1,gammaC | |
Unconjugated | |
Fc Tag | |
Less than 1.0 EU / μg by the LAL method. | |
Powder | |
>95% as determined by SDS-PAGE |