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ACROBiosystems Human IL-18BP Protein, His Tag

MALS verified

315.25 CHF - 1235.79 CHF

Spezifikation

Zugriffsnummer NP_001138529
Molekulargewicht 18.5 kDa
Quelle Human IL-18 BP, His Tag (ILP-H5222) is expressed from human 293 cells (HEK293). It contains AA Thr 31 - Gly 194 (Accession # NP_001138529).
Immunogen Thr 31 - Gly 194
Lagerungsbedingungen -20°C
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Produkte 2
Produktcode Marke Menge Preis Menge & Verfügbarkeit  
Produktcode Marke Menge Preis Menge & Verfügbarkeit  
15837107
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ACROBiosystems
ILP-H5222-200UG
200 μg
315.25 CHF
200 Mikrogramm
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15827107
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ACROBiosystems
ILP-H5222-1MG
1 mg
1235.79 CHF
1 Milligramm
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Verfügbar ab: 07-05-2024
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Beschreibung

Beschreibung

Interleukin-18-binding protein (IL18BP) is also known as Tadekinig-alfa, IL18BPa, which functions as an IL18 inhibitor. IL18BP is a secreted protein which contains one Ig-like C2-type (immunoglobulin-like) domain. IL18BP does not have a transmembrane domain and hence is not anchored to the cell membrane. IL18BP is strongly expressed in heart, lung, placenta and spleen. Isoform A of IL18BP binds to IL-18 and inhibits its activity. IL18BP also functions as an inhibitor of the early TH1 cytokine response. IL18BP suppresses the production of IFN-gamma resulting in reduced T-helper type 1 immune responses.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 18.5 kDa. The protein migrates as 32-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spezifikation

Spezifikation

NP_001138529
Human IL-18 BP, His Tag (ILP-H5222) is expressed from human 293 cells (HEK293). It contains AA Thr 31 - Gly 194 (Accession # NP_001138529).
-20°C
IL-18 BP
Human
PBS, pH7.4
HEK293
Bio-Markers and CD Antigens
18.5 kDa
Thr 31 - Gly 194
IL18BP,IL18BPa,Tadekinig-alfa
Unconjugated
His Tag
Less than 1.0 EU / μg by the LAL method.
Powder
>90% as determined by SDS-PAGE
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

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